[HTML][HTML] Therapeutic targets of neuroprotection and neurorestoration in ischemic stroke: Applications for natural compounds from medicinal herbs

T Zhu, L Wang, L Wang, Q Wan - Biomedicine & Pharmacotherapy, 2022 - Elsevier
Neuroprotective and neurorestorative therapy represent two major drug intervention
strategies for ischemic stroke. Multiple factors such as excitotoxicity, inflammation …

VEGF-A in cardiomyocytes and heart diseases

M Braile, S Marcella, L Cristinziano… - International Journal of …, 2020 - mdpi.com
The vascular endothelial growth factor (VEGF), a homodimeric vasoactive glycoprotein, is
the key mediator of angiogenesis. Angiogenesis, the formation of new blood vessels, is …

A neurovascular-unit-on-a-chip for the evaluation of the restorative potential of stem cell therapies for ischaemic stroke

Z Lyu, J Park, KM Kim, HJ Jin, H Wu… - Nature biomedical …, 2021 - nature.com
The therapeutic efficacy of stem cells transplanted into an ischaemic brain depends primarily
on the responses of the neurovascular unit. Here, we report the development and …

Zwitterionic Polysaccharide‐Based Hydrogel Dressing as a Stem Cell Carrier to Accelerate Burn Wound Healing

Q Yu, H Sun, Z Yue, C Yu, L Jiang… - Advanced …, 2023 - Wiley Online Library
Stem cell therapy integrated with hydrogels has shown promising potential in wound
healing. However, the existing hydrogels usually cannot reach the desired therapeutic …

The evolving role of neuro‐immune interaction in brain repair after cerebral ischemic stroke

X Wang, W Xuan, ZY Zhu, Y Li, H Zhu… - CNS neuroscience & …, 2018 - Wiley Online Library
Stroke is the world's leading cause of disability with limited brain repair treatments which
effectively improve long‐term neurological deficits. The neuroinflammatory responses …

Structural and functional remodeling of the brain vasculature following stroke

M Freitas-Andrade, J Raman-Nair, B Lacoste - Frontiers in physiology, 2020 - frontiersin.org
Maintenance of cerebral blood vessel integrity and regulation of cerebral blood flow ensure
proper brain function. The adult human brain represents only a small portion of the body …

Multipotent mesenchymal stem cell-based therapies for spinal cord injury: current progress and future prospects

CW Zeng - Biology, 2023 - mdpi.com
Simple Summary Mesenchymal stem cells (MSCs) are a promising option for developing
new treatments for spinal cord injury (SCI). They can help repair damaged tissue, making …

A new era of cardiac cell therapy: opportunities and challenges

K Huang, S Hu, K Cheng - Advanced healthcare materials, 2019 - Wiley Online Library
Myocardial infarction (MI), caused by coronary heart disease (CHD), remains one of the
most common causes of death in the United States. Over the last few decades, scientists …

Angiogenesis in ischemic stroke and angiogenic effects of Chinese herbal medicine

SW Seto, D Chang, A Jenkins, A Bensoussan… - Journal of clinical …, 2016 - mdpi.com
Stroke is one of the major causes of death and adult disability worldwide. The underlying
pathophysiology of stroke is highly complicated, consisting of impairments of multiple …

Mesenchymal stem cell therapy for neurological disorders: The light or the dark side of the force?

J Isaković, K Šerer, B Barišić, D Mitrečić - Frontiers in bioengineering …, 2023 - frontiersin.org
Neurological disorders are recognized as major causes of death and disability worldwide.
Because of this, they represent one of the largest public health challenges. With awareness …