Mechanisms of oocyte aneuploidy associated with advanced maternal age

M Mikwar, AJ MacFarlane, F Marchetti - Mutation Research/Reviews in …, 2020 - Elsevier
It is well established that maternal age is associated with a rapid decline in the production of
healthy and high-quality oocytes resulting in reduced fertility in women older than 35 years …

[HTML][HTML] Melatonin mitigates mitochondrial meltdown: interactions with SIRT3

RJ Reiter, DX Tan, S Rosales-Corral, A Galano… - International journal of …, 2018 - mdpi.com
Melatonin exhibits extraordinary diversity in terms of its functions and distribution. When
discovered, it was thought to be uniquely of pineal gland origin. Subsequently, melatonin …

Melatonin enhances mitochondrial biogenesis and protects against rotenone‐induced mitochondrial deficiency in early porcine embryos

YJ Niu, W Zhou, ZW Nie, KT Shin… - Journal of pineal …, 2020 - Wiley Online Library
Melatonin, a major hormone of the pineal gland, exerts many beneficial effects on
mitochondria. Several studies have shown that melatonin can protect against toxin‐induced …

Melatonin supplementation during in vitro maturation of oocyte enhances subsequent development of bovine cloned embryos

Q An, W Peng, Y Cheng, Z Lu, C Zhou… - Journal of cellular …, 2019 - Wiley Online Library
Oocyte quality, which is directly related to reprogramming competence, is a major important
limiting factor in animal cloning efficiency. Compared with oocytes matured in vivo, in vitro …

The role of melatonin, a multitasking molecule, in retarding the processes of ageing

M Majidinia, RJ Reiter, SK Shakouri, B Yousefi - Ageing Research Reviews, 2018 - Elsevier
Biological ageing is generally accompanied by a gradual loss of cellular functions and
physiological integrity of organ systems, the consequential enhancement of vulnerability …

Melatonin regulates the activities of ovary and delays the fertility decline in female animals via MT1/AMPK pathway

L Zhang, Z Zhang, J Wang, D Lv, T Zhu… - Journal of pineal …, 2019 - Wiley Online Library
Female fertility irreversibly declines with aging, and this is primarily associated with the
decreased quality and quantity of oocytes. To evaluate whether a long‐term of melatonin …

Mogroside V improves porcine oocyte in vitro maturation and subsequent embryonic development

J Nie, K Yan, L Sui, H Zhang, H Zhang, X Yang, S Lu… - Theriogenology, 2020 - Elsevier
Oocyte in vitro maturation (IVM) plays a pivotal role in in vitro embryo production. However,
the efficiency of IVM is still low and needs to be further improved. In the present study, we …

[HTML][HTML] In vivo and in vitro postovulatory aging: when time works against oocyte quality?

V Di Nisio, S Antonouli, P Damdimopoulou… - Journal of Assisted …, 2022 - Springer
In mammalian species an optimal fertilization window during which successful fertilization
occurs. In the majority of mammals estrus marks ovulation time and coincident with mating …

[HTML][HTML] Oxidative stress and reproductive function: oxidative stress and in vitro ageing of the post-ovulatory oocyte: an update on recent advances in the field

JH Martin, B Nixon, SL Cafe, RJ Aitken… - …, 2022 - rep.bioscientifica.com
In brief Post-ovulatory ageing of oocytes leads to poor oocyte and embryo quality as well as
abnormalities in offspring. This review provides an update on the contributions of oxidative …

Research progress in green synthesis of manganese and manganese oxide nanoparticles in biomedical and environmental applications–A review

X Zhang, A Sathiyaseelan, KV Naveen, Y Lu, MH Wang - Chemosphere, 2023 - Elsevier
Nanomaterials and nanotechnology have this unassailable position for environmental
remediation and medicine. Currently, global environmental pollution and public health …