Thymol and thyme essential oil—new insights into selected therapeutic applications

A Kowalczyk, M Przychodna, S Sopata, A Bodalska… - Molecules, 2020 - mdpi.com
Thymol (2-isopropyl-5-methylphenol) belongs to the phenolic monoterpenes and mostly
occurs in thyme species. It is one of the main compounds of thyme essential oil. Both thymol …

Cryptococcosis

AC Gushiken, KK Saharia, JW Baddley - Infectious Disease Clinics, 2021 - id.theclinics.com
Cryptococcosis is an infection of global significance, affecting both immunocompromised
and immunocompetent hosts. Traditionally, 2 main species of yeasts caused cryptococcosis …

Fungicide effects on human fungal pathogens: cross-resistance to medical drugs and beyond

RW Bastos, L Rossato, GH Goldman… - PLoS Pathogens, 2021 - journals.plos.org
Fungal infections are underestimated threats that affect over 1 billion people, and Candida
spp., Cryptococcus spp., and Aspergillus spp. are the 3 most fatal fungi. The treatment of …

Fungal pathogens and COVID-19

A Singh, A Kaur, A Chowdhary - Current Opinion in Microbiology, 2023 - Elsevier
COVID-19 pandemic highlighted the complications of secondary fungal infections that
occurred globally in severe cases of coronavirus disease managed in the intensive care …

Clinical manifestations of human exposure to fungi

M Oliveira, D Oliveira, C Lisboa, JL Boechat… - Journal of Fungi, 2023 - mdpi.com
Biological particles, along with inorganic gaseous and particulate pollutants, constitute an
ever-present component of the atmosphere and surfaces. Among these particles are fungal …

A highlight on the inhibition of fungal carbonic anhydrases as drug targets for the antifungal armamentarium

CT Supuran, C Capasso - International Journal of Molecular Sciences, 2021 - mdpi.com
Carbon dioxide (CO2), a vital molecule of the carbon cycle, is a critical component in living
organisms' metabolism, performing functions that lead to the building of compounds …

Emerging animal-associated fungal diseases

JE Carpouron, S de Hoog, E Gentekaki, KD Hyde - Journal of Fungi, 2022 - mdpi.com
The Global Action Fund for Fungal Infections (GAFFI) estimates that fungal diseases kill
around 150 people each hour, and yet they are globally overlooked and neglected …

Searching for new antifungals for the treatment of cryptococcosis

NSO Sousa, JDR Almeida, H Frickmann… - Revista da Sociedade …, 2023 - SciELO Brasil
There is a consensus that the antifungal repertoire for the treatment of cryptococcal
infections is limited. Standard treatment involves the administration of an antifungal drug …

Human airway epithelium responses to invasive fungal infections: A critical partner in innate immunity

AJ Crossen, RA Ward, JL Reedy, MV Surve, BS Klein… - Journal of Fungi, 2022 - mdpi.com
The lung epithelial lining serves as the primary barrier to inhaled environmental toxins,
allergens, and invading pathogens. Pulmonary fungal infections are devastating and carry …

Primary Cutaneous Cryptococcosis Caused by Cryptococcus gatti in an Elderly Patient

W Belda Jr, ATS Casolato, JB Luppi… - Tropical Medicine and …, 2022 - mdpi.com
According to the spread of Cryptococcus sp., fungal infections can be classified as primary
or secondary. In primary cutaneous cryptococcosis, the fungi are restricted to the skin of the …