The oral microbiota: community composition, influencing factors, pathogenesis, and interventions

X Li, Y Liu, X Yang, C Li, Z Song - Frontiers in microbiology, 2022 - frontiersin.org
The human oral cavity provides a habitat for oral microbial communities. The complexity of
its anatomical structure, its connectivity to the outside, and its moist environment contribute …

New strategies and mechanisms for targeting Streptococcus mutans biofilm formation to prevent dental caries: a review

Z Gao, X Chen, C Wang, J Song, J Xu, X Liu… - Microbiological …, 2023 - Elsevier
Dental caries, a prevalent oral infectious disease, is intricately linked to the biofilm formation
on the tooth surfaces by oral microbes. Among these, Streptococcus mutans plays a central …

Safety and efficacy of phage application in bacterial decolonisation: a systematic review

Q Fang, X Yin, Y He, Y Feng, L Zhang, H Luo… - The Lancet …, 2024 - thelancet.com
Colonisation by bacterial pathogens typically precedes invasive infection and seeds
transmission. Thus, effective decolonisation strategies are urgently needed. The literature …

The niche-specialist and age-related oral microbial ecosystem: crosstalk with host immune cells in homeostasis

D Lin, Q Hu, L Yang, X Zeng, Y Xiao… - Microbial …, 2022 - microbiologyresearch.org
Although characterization of the baseline oral microbiota has been discussed, the current
literature seems insufficient to draw a definitive conclusion on the interactions between the …

What are the potential benefits of using bacteriophages in periodontal therapy?

J Kowalski, R Górska, M Cieślik, A Górski… - Antibiotics, 2022 - mdpi.com
Periodontitis, which may result in tooth loss, constitutes both a serious medical and social
problem. This pathology, if not treated, can contribute to the development of, among others …

Antibacterial Activity of a Lysin LysP53 against Streptococcus mutans

X Zhao, C Li, H Yang, H Wei… - Journal of Dental …, 2023 - journals.sagepub.com
Dental caries is a common disease affecting quality of life globally. In the present study, we
found that a bacteriophage lysin LysP53 against Acinetobacter baumannii possesses …

A review and new perspective on oral bacteriophages: manifestations in the ecology of oral diseases

X Guo, X Wang, J Shi, J Ren, J Zeng… - Journal of Oral …, 2024 - Taylor & Francis
Objective To explore the manifestations of bacteriophages in different oral disease
ecologies, including periodontal diseases, dental caries, endodontic infections, and oral …

Biomineral-binding liposomes with dual antibacterial effects for preventing and treating dental caries

Z Luo, Y Lin, X Zhou, L Yang, Z Zhang, Z Liu… - Biomaterials …, 2023 - pubs.rsc.org
Dental caries is a chronic oral disease that results from the demineralization of dental hard
tissues caused by the long-term interaction of various pathogenic factors in the human oral …

Mucosal Environment Induces Phage Susceptibility in Streptococcus mutans

LR Sundberg, N Rantanen… - Therapy, Applications …, 2022 - liebertpub.com
Pathogenic bacteria are attracted toward mucosa, as it is their way of entry into the body.
However, we know surprisingly little about the phage-bacterium interactions in the mucosal …

[HTML][HTML] Isolation of Streptococcus mutans temperate bacteriophage with broad killing activity to S. mutans clinical isolates

K Sugai, M Kawada-Matsuo, MNT Le, Y Sugawara… - Iscience, 2023 - cell.com
Bacteriophages are expected to be therapeutic agents against infectious diseases.
Streptococcus mutans are involved in dental plaque formation related to dental caries and …