[HTML][HTML] GABA concentration in the left ventral premotor cortex associates with sensory hyper-responsiveness in autism spectrum disorders without intellectual …
Y Umesawa, T Atsumi, M Chakrabarty… - Frontiers in …, 2020 - frontiersin.org
Individuals with autism spectrum disorder (ASD) often exhibit abnormal processing of
sensory inputs from multiple modalities and higher-order cognitive/behavioral response to …
sensory inputs from multiple modalities and higher-order cognitive/behavioral response to …
[HTML][HTML] Neuroanatomy and behavior in mice with a haploinsufficiency of AT-rich interactive domain 1B (ARID1B) throughout development
Background One of the causal mechanisms underlying neurodevelopmental disorders
(NDDs) is chromatin modification and the genes that regulate chromatin. AT-rich interactive …
(NDDs) is chromatin modification and the genes that regulate chromatin. AT-rich interactive …
[HTML][HTML] Inhibitory dysfunction and social processing difficulties in autism: A comprehensive narrative review
The primary inhibitory neurotransmitter γ-aminobutyric acid (GABA) has a prominent role in
regulating neural development and function, with disruption to GABAergic signalling linked …
regulating neural development and function, with disruption to GABAergic signalling linked …
[HTML][HTML] Modulation of dorsolateral prefrontal cortex glutamate/glutamine levels following repetitive transcranial magnetic stimulation in young adults with autism
I Moxon-Emre, ZJ Daskalakis, DM Blumberger… - Frontiers in …, 2021 - frontiersin.org
Altered excitatory and inhibitory neurotransmission has been implicated in autism spectrum
disorder (ASD). Interventions using repetitive transcranial magnetic stimulation (rTMS) to …
disorder (ASD). Interventions using repetitive transcranial magnetic stimulation (rTMS) to …
[PDF][PDF] Social deficits via dysregulated Rac1-dependent excitability control of prefrontal cortical neurons and increased GABA/glutamate ratios
B Ma, X Shan, J Yu, T Zhu, R Li, H Lv, H Cheng… - Cell Reports, 2022 - cell.com
Identifying symptom-specific convergent mechanisms for neurodevelopmental disorders is a
promising strategy in advancing therapies. Here, we show that bidirectional dysregulation of …
promising strategy in advancing therapies. Here, we show that bidirectional dysregulation of …
[HTML][HTML] Hippocampal metabolite profiles in two rat models of autism: NMR-based metabolomics studies
B Toczylowska, E Zieminska, P Senator… - Molecular …, 2020 - Springer
Autism spectrum disorders (ASDs) are increasingly being diagnosed. Hypotheses link ASD
to genetic, epigenetic, or environmental factors. The role of oxidative stress and the …
to genetic, epigenetic, or environmental factors. The role of oxidative stress and the …
[HTML][HTML] Vitamin C attenuates oxidative stress and behavioral abnormalities triggered by fipronil and pyriproxyfen insecticide chronic exposure on zebrafish juvenile
Chronic exposure to synthetic insecticides in the early life of a child can lead to a series of
disorders. Several causes as parental age, maternal smoking, birth complications, and …
disorders. Several causes as parental age, maternal smoking, birth complications, and …
[HTML][HTML] Preliminary results regarding sleep in a zebrafish model of autism spectrum disorder
Autism spectrum disorder (ASD) is one of the most salient developmental neurological
diseases and remarkable similarities have been found between humans and model animals …
diseases and remarkable similarities have been found between humans and model animals …
Effects of single-dose antipurinergic therapy on behavioral and molecular alterations in the valproic acid-induced animal model of autism
MM Hirsch, I Deckmann, J Santos-Terra, GZ Staevie… - …, 2020 - Elsevier
Autism spectrum disorder (ASD) is characterized by deficits in communication and social
interaction, restricted interests, and stereotyped behavior. Environmental factors, such as …
interaction, restricted interests, and stereotyped behavior. Environmental factors, such as …
[HTML][HTML] Behavioral aspects and neurobiological properties underlying medical cannabis treatment in Shank3 mouse model of autism spectrum disorder
Autism spectrum disorder (ASD) is a neurodevelopmental disease with a wide spectrum of
manifestation. The core symptoms of ASD are persistent deficits in social communication …
manifestation. The core symptoms of ASD are persistent deficits in social communication …