Behavioral aspects and neurobiological properties underlying medical cannabis treatment in Shank3 mouse model of autism spectrum disorder

S Poleg, E Kourieh, A Ruban, G Shapira… - Translational …, 2021 - nature.com
Autism spectrum disorder (ASD) is a neurodevelopmental disease with a wide spectrum of
manifestation. The core symptoms of ASD are persistent deficits in social communication …

[HTML][HTML] Meta-analysis and open-source database for in vivo brain Magnetic Resonance spectroscopy in health and disease

AT Gudmundson, A Koo, A Virovka, AL Amirault… - Analytical …, 2023 - Elsevier
Abstract Proton (1 H) Magnetic Resonance Spectroscopy (MRS) is a non-invasive tool
capable of quantifying brain metabolite concentrations in vivo. Prioritization of …

GABA concentration in the left ventral premotor cortex associates with sensory hyper-responsiveness in autism spectrum disorders without intellectual disability

Y Umesawa, T Atsumi, M Chakrabarty… - Frontiers in …, 2020 - frontiersin.org
Individuals with autism spectrum disorder (ASD) often exhibit abnormal processing of
sensory inputs from multiple modalities and higher-order cognitive/behavioral response to …

[HTML][HTML] Ketamine administration in early postnatal life as a tool for mimicking Autism Spectrum Disorders core symptoms

M Bove, S Schiavone, P Tucci, V Sikora… - Progress in Neuro …, 2022 - Elsevier
Abstract Autism Spectrum Disorders (ASD) core symptoms include deficits of social
interaction, stereotyped behaviours, dysfunction in language and communication. Beyond …

Astrotactin 2 (ASTN2) regulates emotional and cognitive functions by affecting neuronal morphogenesis and monoaminergic systems

T Ito, M Yoshida, T Aida, I Kushima… - Journal of …, 2023 - Wiley Online Library
Abstract Astrotactin2 (ASTN2) regulates neuronal migration and synaptic strength through
the trafficking and degradation of surface proteins. Deletion of ASTN2 in copy number …

The cortico-striatal circuitry in autism-spectrum disorders: a balancing act

JJ Soghomonian - Frontiers in Cellular Neuroscience, 2024 - frontiersin.org
The basal ganglia are major targets of cortical inputs and, in turn, modulate cortical function
via their projections to the motor and prefrontal cortices. The role of the basal ganglia in …

Modulation of dorsolateral prefrontal cortex glutamate/glutamine levels following repetitive transcranial magnetic stimulation in young adults with autism

I Moxon-Emre, ZJ Daskalakis, DM Blumberger… - Frontiers in …, 2021 - frontiersin.org
Altered excitatory and inhibitory neurotransmission has been implicated in autism spectrum
disorder (ASD). Interventions using repetitive transcranial magnetic stimulation (rTMS) to …

GABAB Receptor Agonist R-Baclofen Reverses Altered Auditory Reactivity and Filtering in the Cntnap2 Knock-Out Rat

D Möhrle, W Wang, SN Whitehead… - Frontiers in Integrative …, 2021 - frontiersin.org
Altered sensory information processing, and auditory processing, in particular, is a common
impairment in individuals with autism spectrum disorder (ASD). One prominent hypothesis …

[HTML][HTML] Inhibitory dysfunction and social processing difficulties in autism: A comprehensive narrative review

NF Parrella, AT Hill, LM Dipnall, YJ Loke… - Journal of Psychiatric …, 2023 - Elsevier
The primary inhibitory neurotransmitter γ-aminobutyric acid (GABA) has a prominent role in
regulating neural development and function, with disruption to GABAergic signalling linked …

Preliminary results regarding sleep in a zebrafish model of autism spectrum disorder

MA Robea, A Ciobica, AS Curpan, G Plavan… - Brain sciences, 2021 - mdpi.com
Autism spectrum disorder (ASD) is one of the most salient developmental neurological
diseases and remarkable similarities have been found between humans and model animals …