Whole-transcriptome analysis of serum L1CAM-captured extracellular vesicles reveals neural and glycosylation changes in autism spectrum disorder

Y Qin, L Cao, J Zhang, H Zhang, S Cai, B Guo… - Journal of Molecular …, 2022 - Springer
The pathophysiology of autistic spectrum disorder (ASD) is not fully understood and there
are no diagnostic or predictive biomarkers. Extracellular vesicles (EVs) are cell-derived …

The lack of alterations in metabolites in the medial prefrontal cortex and amygdala, but their associations with autistic traits, empathy, and personality traits in adults …

Y Shirayama, K Matsumoto, F Osone, A Hara… - Journal of Autism and …, 2024 - Springer
Proton magnetic resonance spectroscopy (1H-MRS) has shown inconsistent alterations in
brain metabolites of adults with autism spectrum disorder (ASD). We investigated brain …

Trained innate immunity not always amicable

M Włodarczyk, M Druszczyńska, M Fol - International Journal of …, 2019 - mdpi.com
The concept of “trained innate immunity” is understood as the ability of innate immune cells
to remember invading agents and to respond nonspecifically to reinfection with increased …

Association of anemia with neurodevelopmental disorders in a nationally representative sample of US children

W Yang, B Liu, R Gao, LG Snetselaar… - The Journal of …, 2021 - Elsevier
Objective To examine the associations of anemia with autism spectrum disorder (ASD),
attention deficit hyperactivity disorder (ADHD), and learning disability in US children. Study …

Dysfunctional d-aspartate metabolism in BTBR mouse model of idiopathic autism

T Nuzzo, M Sekine, D Punzo, M Miroballo… - … et Biophysica Acta (BBA …, 2020 - Elsevier
Background Autism spectrum disorders (ASD) comprise a heterogeneous group of
neurodevelopmental conditions characterized by impairment in social interaction, deviance …

Hippocampal metabolite profiles in two rat models of autism: NMR-based metabolomics studies

B Toczylowska, E Zieminska, P Senator… - Molecular …, 2020 - Springer
Autism spectrum disorders (ASDs) are increasingly being diagnosed. Hypotheses link ASD
to genetic, epigenetic, or environmental factors. The role of oxidative stress and the …

The gut-brain axis in autism spectrum disorder: a focus on the metalloproteases ADAM10 and ADAM17

Y Zheng, TA Verhoeff, P Perez Pardo… - International Journal of …, 2020 - mdpi.com
Autism Spectrum Disorder (ASD) is a spectrum of disorders that are characterized by
problems in social interaction and repetitive behavior. The disease is thought to develop …

The “primitive brain dysfunction” theory of autism: the superior colliculus role

R Jure - Frontiers in Integrative Neuroscience, 2022 - frontiersin.org
A better understanding of the pathogenesis of autism will help clarify our conception of the
complexity of normal brain development. The crucial deficit may lie in the postnatal changes …

A magnetic resonance spectroscopy study of superior visual search abilities in children with autism spectrum disorder

DA Edmondson, P Xia, R McNally Keehn… - Autism …, 2020 - Wiley Online Library
Although diagnosed on the basis of deficits in social communication and interaction, autism
spectrum disorder (ASD) is also characterized by superior performance on a variety of …

Homogeneous intrinsic neuronal excitability induces overfitting to sensory noise: A robot model of neurodevelopmental disorder

H Idei, S Murata, Y Yamashita, T Ogata - Frontiers in Psychiatry, 2020 - frontiersin.org
Neurodevelopmental disorders, including autism spectrum disorder, have been intensively
investigated at the neural, cognitive, and behavioral levels, but the accumulated knowledge …