Background Ketamine appears to have a therapeutic role in certain mental disorders, most
notably depression. However, the comparative performance of different formulations of …

Background: The management of acute and chronic pain for individuals living with sickle cell
disease (SCD) is a clinical challenge. This reflects the paucity of clinical SCD pain research …

Background Ketamine infusions have been used for decades to treat acute pain, but a
recent surge in usage has made the infusions a mainstay of treatment in emergency …

Background The past two decades have witnessed a surge in the use of lumbar facet blocks
and radiofrequency ablation (RFA) to treat low back pain (LBP), yet nearly all aspects of the …

Current medication for anxiety disorders is suboptimal in terms of efficiency and tolerability,
highlighting the need for improved drug treatments. In this review an overview of drugs …

Background The past two decades have witnessed a surge in the use of cervical spine joint
procedures including joint injections, nerve blocks and radiofrequency ablation to treat …

Effective prevention of chronic postoperative pain is an important clinical goal, informed by a
growing body of studies. Peri‐operative regional anaesthesia remains one of the most …

Objectif: Les patients souffrant de trouble dépressif majeur (TDM) ont souvent une réponse
limitée aux médicaments de première et de deuxième intention, donc de nouveaux …

Background The past two decades have witnessed an epidemic of opioid use disorder
(OUD) in the USA, resulting in catastrophic loss of life secondary to opioid overdoses …

BACKGROUND: IV ketamine is widely used to treat patients with chronic pain, yet the long-
term impact remains uncertain. We synthesized evidence from randomized control trials to …