Hippocampal sclerosis in epilepsy: a neuropathology review
M Thom - Neuropathology and applied neurobiology, 2014 - Wiley Online Library
Hippocampal sclerosis (HS) is a common pathology encountered in mesial temporal lobe
epilepsy (MTLE) as well as other epilepsy syndromes and in both surgical and post‐mortem …
epilepsy (MTLE) as well as other epilepsy syndromes and in both surgical and post‐mortem …
An update for epilepsy research and antiepileptic drug development: Toward precise circuit therapy
Y Wang, Z Chen - Pharmacology & therapeutics, 2019 - Elsevier
Epilepsy involves neuronal dysfunction at molecular, cellular, and circuit levels. The
understanding of the mechanism of the epilepsies has advanced greatly in the last three …
understanding of the mechanism of the epilepsies has advanced greatly in the last three …
Epilepsy: new advances
Epilepsy affects 65 million people worldwide and entails a major burden in seizure-related
disability, mortality, comorbidities, stigma, and costs. In the past decade, important advances …
disability, mortality, comorbidities, stigma, and costs. In the past decade, important advances …
A sensitive and specific nanosensor for monitoring extracellular potassium levels in the brain
Extracellular potassium concentration affects the membrane potential of neurons, and, thus,
neuronal activity. Indeed, alterations of potassium levels can be related to neurological …
neuronal activity. Indeed, alterations of potassium levels can be related to neurological …
Forecasting stroke-like episodes and outcomes in mitochondrial disease
In this retrospective, multicentre, observational cohort study, we sought to determine the
clinical, radiological, EEG, genetics and neuropathological characteristics of mitochondrial …
clinical, radiological, EEG, genetics and neuropathological characteristics of mitochondrial …
[PDF][PDF] Expression of the neuronal tRNA n-Tr20 regulates synaptic transmission and seizure susceptibility
The mammalian genome has hundreds of nuclear-encoded tRNAs, but the contribution of
individual tRNA genes to cellular and organismal function remains unknown. Here, we …
individual tRNA genes to cellular and organismal function remains unknown. Here, we …
[HTML][HTML] Increased segregation of brain networks in focal epilepsy: an fMRI graph theory finding
Focal epilepsy is conceived of as activating local areas of the brain as well as engaging
regional brain networks. Graph theory represents a powerful quantitative framework for …
regional brain networks. Graph theory represents a powerful quantitative framework for …
Role of the Fyn-PKCδ signaling in SE-induced neuroinflammation and epileptogenesis in experimental models of temporal lobe epilepsy
Status epilepticus (SE) induces neuroinflammation and epileptogenesis, but the
mechanisms are not yet fully delineated. The Fyn, a non-receptor Src family tyrosine kinase …
mechanisms are not yet fully delineated. The Fyn, a non-receptor Src family tyrosine kinase …
Chimera states in hybrid coupled neuron populations
Here we study the emergence of chimera states, a recently reported phenomenon referring
to the coexistence of synchronized and unsynchronized dynamical units, in a population of …
to the coexistence of synchronized and unsynchronized dynamical units, in a population of …
[HTML][HTML] Vagus nerve stimulation elicits sleep EEG desynchronization and network changes in responder patients in epilepsy
Neural desynchronization was shown as a key mechanism of vagus nerve stimulation (VNS)
action in epilepsy, and EEG synchronization measures are explored as possible response …
action in epilepsy, and EEG synchronization measures are explored as possible response …