The neurotransmitter molecule acetylcholine is capable of activating five muscarinic
acetylcholine receptors, M1 through M5, which belong to the superfamily of G-protein …

Glycans on the host cell membrane and viral proteins play critical roles in pathogenesis.
Highly glycosylated epithelial cells represent the primary boundary separating embedded …

Introduction Salmonella is responsible for causing enteric fever, septicemia, and
gastroenteritis in humans. Due to high disease burden and emergence of multi-and …

Atomic-level structural insight on the human ABCG2 membrane protein, a pharmacologically
important transporter, has been recently revealed by several key papers. In spite of the …

Numerous repositioned drugs have been sought to decrease the severity of SARS-CoV-2
infection. It is known that among its physicochemical properties, Ursodeoxycholic Acid …

The double electron–electron resonance (DEER) is a powerful structural biology technique
to obtain distance information in the range of 18 to 80 å by measuring the dipolar coupling …

Abstract We present BioExcel Building Blocks Workflows, a web-based graphical user
interface (GUI) offering access to a collection of transversal pre-configured biomolecular …

Background HIV-1 produces Tat, a crucial protein for transcription, viral replication, and CNS
neurotoxicity. Tat interacts with TAR, enhancing HIV reverse transcription. Subtype C Tat …

Human immunoglobulin G subclass 3 (IgG3) possesses a uniquely long hinge region that
separates its Fab antigen-binding and Fc receptor-binding regions. Owing to this hinge …

The synergistic conjunction of various technological revolutions with the accumulated
knowledge and workflows is rapidly transforming several scientific fields. Particularly …