Targeting the Wnt/β-catenin signaling pathway in cancer

Y Zhang, X Wang - Journal of hematology & oncology, 2020 - Springer
The aberrant Wnt/β-catenin signaling pathway facilitates cancer stem cell renewal, cell
proliferation and differentiation, thus exerting crucial roles in tumorigenesis and therapy …

[HTML][HTML] Lipid alterations in chronic liver disease and liver cancer

B Paul, M Lewinska, JB Andersen - JHEP reports, 2022 - Elsevier
Lipids are a complex and diverse group of molecules with crucial roles in many
physiological processes, as well as in the onset, progression, and maintenance of cancers …

Advances in anti-cancer effects and underlying mechanisms of marine algae polysaccharides

W Yao, HM Qiu, KL Cheong, S Zhong - International Journal of Biological …, 2022 - Elsevier
Cancer is a leading cause of death in both developing and developed countries. With the
increase in the average global life expectancy, it has become a major health problem and …

Hepatocellular carcinoma: molecular mechanism, targeted therapy, and biomarkers

Y Wang, B Deng - Cancer and Metastasis Reviews, 2023 - Springer
Hepatocellular carcinoma (HCC) is a common malignancy and one of the leading causes of
cancer-related death. The biological process of HCC is complex, with multiple factors …

Combining crocin and sorafenib improves their tumor-inhibiting effects in a rat model of diethylnitrosamine-induced cirrhotic-hepatocellular carcinoma

B Awad, AA Hamza, A Al-Maktoum, S Al-Salam, A Amin - Cancers, 2023 - mdpi.com
Simple Summary Liver cancer represents one of the most lethal forms of cancer, with
hepatocellular carcinoma (HCC) accounting for the majority of its incidences and deaths …

[HTML][HTML] Embolization therapy with microspheres for the treatment of liver cancer: State-of-the-art of clinical translation

A Pérez-López, C Martín-Sabroso, L Gómez-Lázaro… - Acta Biomaterialia, 2022 - Elsevier
Embolization with microspheres is a therapeutic strategy based on the selective occlusion of
the blood vessels feeding a tumor. This procedure is intraarterially performed in the clinical …

Wnt pathway modulators in cancer therapeutics: An update on completed and ongoing clinical trials

A Neiheisel, M Kaur, N Ma, P Havard… - … Journal of Cancer, 2022 - Wiley Online Library
Wnt signaling plays an essential role in the initiation and progression of various types of
cancer. Besides, the Wnt pathway components have been established as reliable …

Chronic kidney disease and cancer: inter-relationships and mechanisms

M Hu, Q Wang, B Liu, Q Ma, T Zhang… - Frontiers in Cell and …, 2022 - frontiersin.org
Chronic kidney disease (CKD) has been recognized as an increasingly serious public
health problem globally over the decades. Accumulating evidence has shown that the …

MYBL2 promotes proliferation and metastasis of bladder cancer through transactivation of CDCA3

W Liu, D Shen, L Ju, R Zhang, W Du, W Jin, K Xiong… - Oncogene, 2022 - nature.com
The transcription factor MYB proto-oncogene like 2 (MYBL2) is critical in regulating gene
expression and tumorigenesis. However, the biological function of MYBL2 in bladder cancer …

Curcumin in the treatment of liver cancer: From mechanisms of action to nanoformulations

SI Shelash AlHawary… - Phytotherapy …, 2023 - Wiley Online Library
Liver cancer is the sixth most prevalent cancer and ranks third in cancerrelated death, after
lung and colorectal cancer. Various natural products have been discovered as alternatives …