Early endothelial signaling transduction in developing lung edema

G Miserocchi - Life, 2023 - mdpi.com
The lung promptly responds to edemagenic conditions through functional adaptations that
contrast the increase in microvascular filtration. This review presents evidence for early …

Effects of tocilizumab and dexamethasone on the downregulation of proinflammatory cytokines and upregulation of antioxidants in the lungs in oleic acid-induced …

F Terzi, B Demirci, İ Çınar, M Alhilal, HS Erol - Respiratory research, 2022 - Springer
Background Acute respiratory distress syndrome (ARDS) is a life-threatening disease
caused by the induction of inflammatory cytokines and chemokines in the lungs. There is a …

STC3141 improves acute lung injury through neutralizing circulating histone in rat with experimentally-induced acute respiratory distress syndrome

Y Ge, C Wang, C Yao, Y Wang, Y Zheng… - Frontiers in …, 2023 - frontiersin.org
Background: Acute respiratory distress syndrome (ARDS) remains a challenge because of
its high morbidity and mortality. Circulation histones levels in ARDS patients were correlated …

SIS3 suppresses osteoclastogenesis and ameliorates bone loss in ovariectomized mice by modulating Nox4-dependent reactive oxygen species

W Pan, L Zheng, J Gao, L Ye, Z Chen, S Liu… - Biochemical …, 2022 - Elsevier
Osteoporosis is a metabolic disorder of reduced bone mass, accompanied by the
deterioration of the bone microstructure, resulting in increased brittleness and easy fracture …

N-Acetylcysteine in Mechanically Ventilated Rats with Lipopolysaccharide-Induced Acute Respiratory Distress Syndrome: The Effect of Intravenous Dose on …

M Kolomaznik, P Mikolka, J Hanusrichterova… - Biomedicines, 2021 - mdpi.com
Treatment of acute respiratory distress syndrome (ARDS) is challenging due to its
multifactorial aetiology. The benefit of antioxidant therapy was not consistently demonstrated …

Extracts of Periplaneta americana alleviate hepatic fibrosis by affecting hepatic TGF-β and NF-κB expression in rats with pig serum-induced liver fibrosis

D Li, D Ma, Y Liu, L Liu, Y Chen, H Liu… - Folia Histochemica …, 2022 - journals.viamedica.pl
Introduction. Liver fibrosis is caused by continuous wound healing responses to various
harmful stimuli, including viral infection, drugs, alcohol, and autoimmune liver disease. The …

Significance of pyroptosis in immunoregulation and prognosis of patients with acute respiratory distress syndrome: evidence from RNA-Seq of alveolar macrophages

B Liu, Y Li, J Xiang, Y Li, M Zhou, Y Ren… - Journal of …, 2023 - Taylor & Francis
Objective This study aimed to investigate the role of pyroptosis in alveolar macrophages
regarding the immune microenvironment of acute respiratory distress syndrome (ARDS) and …

[HTML][HTML] Alveolar repair following LPS-induced injury requires cell-ECM interactions

JMS Sucre, F Bock, NM Negretti, JT Benjamin… - JCI insight, 2023 - ncbi.nlm.nih.gov
During alveolar repair, alveolar type 2 (AT2) epithelial cell progenitors rapidly proliferate and
differentiate into flat AT1 epithelial cells. Failure of normal alveolar repair mechanisms can …

Integration of multiomics analysis to reveal the major pathways of vitamin A deficiency aggravates acute respiratory distress syndrome in neonatal rats

J Tang, J Yuan, J Sun, M Yan, M Li, Y Liu, S Xu, J Li… - Scientific Reports, 2023 - nature.com
Acute respiratory distress syndrome (ARDS) is a major disease that threatens the life and
health of neonates. Vitamin A (VA) can participate in early fetal lung development and affect …

Hippophae rhamnoides Prevents Oleic Acid-Induced Acute Respiratory Distress Syndrome by Releasing Acetylcholinesterase Activity and Mitigation of Angiotensin …

K Koc - Journal of Medicinal Food, 2024 - liebertpub.com
Hippophae rhamnoides exhibit a wide variety of medicinal and pharmacological effects. The
present study aims to determine the role of ethanol extract of H. rhamnoides on oleic acid …