Resolving lineage relationships between cells in an organism is a fundamental interest of
developmental biology. Furthermore, investigating lineage can drive understanding of …

The major β‐haemoglobinopathies, sickle cell disease and β‐thalassaemia, represent the
most common monogenic disorders worldwide and a steadily increasing global disease …

The human brain is subdivided into distinct anatomical structures, including the neocortex,
which in turn encompasses dozens of distinct specialized cortical areas. Early …

The development of neural circuits relies on axon projections establishing diverse, yet well-
defined, connections between areas of the nervous system. Each projection is formed by …

The cerebral cortex executes highly skilled movement, necessitating that it connects
accurately with specific brainstem and spinal motor circuitry. Corticospinal neurons (CSN) …

Appropriate histone modifications emerge as essential cell fate regulators of neuronal
identities across neocortical areas and layers. Here we showed that NSD1, the …

For half a century now, the barrel cortex of common laboratory rodents has been an
exceptionally useful model for studying the formation of topographically organized maps …

For precise motor control, distinct subpopulations of corticospinal neurons (CSN) must
extend axons to distinct spinal segments, from proximal targets in the brainstem and cervical …

The assembly and maturation of the mammalian brain result from an intricate cascade of
highly coordinated developmental events, such as cell proliferation, migration, and …

Transcription factors regulate multiple processes during brain development and in the adult
brain, from brain patterning to differentiation and maturation of highly specialized neurons as …