Owing to their unique chemical and physical properties, hydrogels are attracting increasing
attention in both basic and translational biomedical studies. Although the classical hydrogels …

In spite of the considerable achievements in the field of regenerative medicine in the past
several decades, osteochondral defect regeneration remains a challenging issue among …

Tissue engineering has become a promising strategy for repairing damaged cartilage and
bone tissue. Among the scaffolds for tissue-engineering applications, injectable hydrogels …

The hyaline cartilage is the most abundant type of cartilage in the body. It is responsible for
the bone formation in the embryo (endochondral ossification) and in adults, it can be found …

Fox et al Nov• Dec 2009 of articular cartilage thickness. The collagen fibers of this zone
(primarily, type II and IX collagen) are packed tightly and aligned parallel to the articular …

Painful degeneration of soft tissues accounts for high socioeconomic costs. Tissue
engineering aims to provide biomimetics recapitulating native tissues. Biocompatible …

Tissue engineering often uses synthetic scaffolds to direct cell responses during engineered
tissue development. Since cells reside within specific niches of the extracellular matrix, it is …

Poly (glycerol sebacate)(PGS) is a biodegradable polymer increasingly used in a variety of
biomedical applications. This polyester is prepared by polycondensation of glycerol and …

The in vivo pathomechanics of osteoarthritis (OA) at the knee is described in a framework
that is based on an analysis of studies describing assays of biomarkers, cartilage …

The discovery of electric fields in biological tissues has led to efforts in developing
technologies utilizing electrical stimulation for therapeutic applications. Native tissues, such …