PTEN inhibition attenuates endothelial cell apoptosis in coronary heart disease via modulating the AMPK–CREB–Mfn2‐mitophagy signaling pathway

P Li, J Wang, X Zhao, J Ru, T Tian, Y An… - Journal of Cellular …, 2020 - Wiley Online Library
Atherosclerosis (AS) is a major pathogenic factor in patients with cardiovascular diseases,
and endothelial dysfunction (ED) plays a primary role in the occurrence and development of …

A TaSnRK1α Modulates TaPAP6L‐Mediated Wheat Cold Tolerance through Regulating Endogenous Jasmonic Acid

L Zhang, N Zhang, S Wang, H Tian, L Liu… - Advanced …, 2023 - Wiley Online Library
Here, a sucrose non‐fermenting‐1‐related protein kinase alpha subunit (TaSnRK1α‐1A) is
identified as associated with cold stress through integration of genome‐wide association …

Melatonin enhances metallic oxide nanoparticle stress tolerance in rice via inducing tetrapyrrole biosynthesis and amino acid metabolism

Y Song, B Wang, D Qiu, Z Xie, S Dai, C Li… - Environmental …, 2021 - pubs.rsc.org
The overuse of metallic oxide nanoparticles (NPs) has caused a burst of their enrichment in
paddy fields. Several findings have reported that the NPs of ZnO and CuO have an adverse …

The pathway of melatonin biosynthesis in common wheat (Triticum aestivum)

J Chen, Y Zhang, H Yin, W Liu, X Hu… - Journal of Pineal …, 2023 - Wiley Online Library
Melatonin (Mel) is a multifunctional biomolecule found in both animals and plants. In plants,
the biosynthesis of Mel from tryptophan (Trp) has been delineated to comprise of four …

Exogenous Melatonin and CaCl2 Alleviate Cold-Induced Oxidative Stress and Photosynthetic Inhibition in Cucumber Seedlings

C Ma, ZQ Pei, X Bai, SH Lu, M Su, X Kang… - Journal of Plant Growth …, 2023 - Springer
Abstract Melatonin (Mel) and CaCl2 have been demonstrated to play significant roles in
plant cold tolerance. However, studies on their mechanisms of action are relatively limited. In …

Genetic engineering of the biosynthesis of glycinebetaine enhances the fruit development and size of tomato

T Zhang, J Liang, M Wang, D Li, Y Liu, THH Chen… - Plant Science, 2019 - Elsevier
Glycinebetaine has been widely considered as an effective protectant against abiotic stress
in plants, and also found to promote plant growth under normal growing conditions …

Melatonin promotes potassium deficiency tolerance by regulating HAK1 transporter and its upstream transcription factor NAC71 in wheat

GZ Li, J Liu, SJ Chen, PF Wang, HT Liu… - Journal of Pineal …, 2021 - Wiley Online Library
Melatonin (MT) is involved in various physiological processes and stress responses in
animals and plants. However, little is known about the molecular mechanisms by which MT …

Renal tubular cell death and inflammation response are regulated by the MAPK-ERK-CREB signaling pathway under hypoxia-reoxygenation injury

Q Dong, Y Jie, J Ma, C Li, T Xin… - Journal of Receptors and …, 2019 - Taylor & Francis
Context: Cell death and inflammation response have been found to the primary features of
acute kidney injury. Objective: The aim of our study is to figure out the molecular mechanism …

Ameliorative roles of melatonin and/or zeolite on chromium-induced leaf senescence in marjoram plants by activating antioxidant defense, osmolyte accumulation …

S Farouk, SM Al-Amri - Industrial Crops and Products, 2019 - Elsevier
Growing medicinal herbs on chromium-rich soils can pose severe threats to humans,
animals, plants, and ecosystems. Leaf senescence is a typical sign of chromium …

Inhibitory effect of melatonin on Mst1 ameliorates myocarditis through attenuating ER stress and mitochondrial dysfunction

H Ouyang, J Zhong, J Lu, Y Zhong, Y Hu… - Journal of molecular …, 2019 - Springer
Viral myocarditis has been found to be one of the leading causes of sudden death in young
adults. However, no effective drugs have been developed to intervene the progression of …