[HTML][HTML] Writing, erasing and reading histone lysine methylations

K Hyun, J Jeon, K Park, J Kim - Experimental & molecular medicine, 2017 - nature.com
Histone modifications are key epigenetic regulatory features that have important roles in
many cellular events. Lysine methylations mark various sites on the tail and globular …

The COMPASS family of histone H3K4 methylases: mechanisms of regulation in development and disease pathogenesis

A Shilatifard - Annual review of biochemistry, 2012 - annualreviews.org
The Saccharomyces cerevisiae Set1/COMPASS was the first histone H3 lysine 4 (H3K4)
methylase identified over 10 years ago. Since then, it has been demonstrated that …

SET for life: biochemical activities and biological functions of SET domain-containing proteins

HM Herz, A Garruss, A Shilatifard - Trends in biochemical sciences, 2013 - cell.com
SET domain-containing proteins belong to a group of enzymes named after a common
domain that utilizes the cofactor S-adenosyl-L-methionine (SAM) to achieve methylation of …

[HTML][HTML] Determinants of histone H3K4 methylation patterns

LM Soares, PC He, Y Chun, H Suh, TS Kim… - Molecular cell, 2017 - cell.com
Various factors differentially recognize trimethylated histone H3 lysine 4 (H3K4me3) near
promoters, H3K4me2 just downstream, and promoter-distal H3K4me1 to modulate gene …

Increase in Tomato Locule Number Is Controlled by Two Single-Nucleotide Polymorphisms Located Near WUSCHEL

S Munos, N Ranc, E Botton, A Bérard… - Plant …, 2011 - academic.oup.com
In tomato (Solanum lycopersicum) fruit, the number of locules (cavities containing seeds that
are derived from carpels) varies from two to up to 10 or more. Locule number affects fruit …

The Paf1 complex: a keystone of nuclear regulation operating at the interface of transcription and chromatin

AM Francette, SA Tripplehorn, KM Arndt - Journal of molecular biology, 2021 - Elsevier
The regulation of transcription by RNA polymerase II is closely intertwined with the
regulation of chromatin structure. A host of proteins required for the disassembly …

Ubiquitin and proteasomes in transcription

F Geng, S Wenzel, WP Tansey - Annual review of biochemistry, 2012 - annualreviews.org
Regulation of gene transcription is vitally important for the maintenance of normal cellular
homeostasis. Failure to correctly regulate gene expression, or to deal with problems that …

Epigenome manipulation as a pathway to new natural product scaffolds and their congeners

RH Cichewicz - Natural product reports, 2010 - pubs.rsc.org
Covering: up to the end of September 2009 The covalent modification of chromatin is an
important control mechanism used by fungi to modulate the transcription of genes involved …

[HTML][HTML] H3 lysine 4 is acetylated at active gene promoters and is regulated by H3 lysine 4 methylation

B Guillemette, P Drogaris, HHS Lin, H Armstrong… - PLoS …, 2011 - journals.plos.org
Methylation of histone H3 lysine 4 (H3K4me) is an evolutionarily conserved modification
whose role in the regulation of gene expression has been extensively studied. In contrast …

[HTML][HTML] Disengaging polymerase: terminating RNA polymerase II transcription in budding yeast

HE Mischo, NJ Proudfoot - Biochimica et Biophysica Acta (BBA)-Gene …, 2013 - Elsevier
Termination of transcription by RNA polymerase II requires two distinct processes: The
formation of a defined 3′ end of the transcribed RNA, as well as the disengagement of RNA …