Bacterial pneumonia greatly contributes to the disease burden and mortality of lower
respiratory tract infections among all age groups and risk profiles. Therefore, laboratory …

Pseudomonas aeruginosa is one of the leading invasive agents of human pulmonary
infection, especially in patients with compromised immunity. Prior studies have used various …

Histological and lineage immunofluorescence examination revealed that healthy conducting
airways of humans and animals harbor sporadic poorly differentiated epithelial patches …

Acute lung injury (ALI) is a major pathological problem characterized by severe inflammatory
reactions and is a critical disease with high clinical morbidity and mortality. Liensinine, a …

Background The airway epithelium plays a central role in the pathogenesis of chronic
respiratory diseases such as asthma and chronic rhinosinusitis with nasal polyps …

Hermansky-Pudlak syndrome (HPS) types 1 and 4 are caused by defective vesicle
trafficking. The mechanism for Crohn's disease-like inflammation, lung fibrosis, and …

Acute lung injury (ALI) is characterized by acute systemic inflammatory responses that may
lead to severe acute respiratory distress syndrome (ARDS). The clinical course of ALI/ARDS …

Developing new adjuvants/vaccines and better understanding their mode-of-action is an
important task. To specifically improve birch pollen allergy treatment, we designed a fusion …

DNA methyltransferase (Dnmt) 3b mediates de novo DNA methylation and modulation of
Dnmt3b in respiratory epithelial cells has been shown to affect the expression of multiple …

Due to optimised treatment strategies and the availability of new therapies during the last
decades, formerly devastating chronic inflammatory diseases such as rheumatoid arthritis or …