Comparative pathology of dog and human prostate cancer
T Ryman‐Tubb, JH Lothion‐Roy… - Veterinary medicine …, 2022 - Wiley Online Library
Though relatively rare in dogs, prostate cancer (PCa) is the most common non‐cutaneous
cancer in men. Human and canine prostate glands share many functional, anatomical and …
cancer in men. Human and canine prostate glands share many functional, anatomical and …
[HTML][HTML] Advances in organoid technology for veterinary disease modeling
B Chen, RF Slocombe, SR Georgy - Frontiers in Veterinary …, 2023 - ncbi.nlm.nih.gov
Organoids are in vitro organ-like structures that faithfully recapitulate many characteristics of
a specific organ. During the past decades, major progress has been accomplished in …
a specific organ. During the past decades, major progress has been accomplished in …
MDR1 inhibition reverses doxorubicin-resistance in six doxorubicin-resistant canine prostate and bladder cancer cell lines
EM Packeiser, L Engels, I Nolte… - International Journal of …, 2023 - mdpi.com
Acquired chemoresistance during chemotherapy, often accompanied by cross-and multi-
resistance, limits therapeutic outcomes and leads to recurrence. In order to create in vitro …
resistance, limits therapeutic outcomes and leads to recurrence. In order to create in vitro …
An RNA-Seq-based framework for characterizing canine prostate cancer and prioritizing clinically relevant biomarker candidate genes
H Thiemeyer, L Taher, JT Schille, EM Packeiser… - International journal of …, 2021 - mdpi.com
Prostate cancer (PCa) in dogs is a highly malignant disease akin to its human counterpart. In
contrast to the situation in humans, multi-gene approaches facilitating risk stratification of …
contrast to the situation in humans, multi-gene approaches facilitating risk stratification of …
[HTML][HTML] Metformin and sodium dichloroacetate effects on proliferation, apoptosis, and metabolic activity tested alone and in combination in a canine prostate and a …
K Klose, EM Packeiser, P Müller, JL Granados-Soler… - PLoS …, 2021 - journals.plos.org
An important approach in tumor therapy is combining substances with different action
mechanisms aiming to enhance the antineoplastic effect, decrease the therapeutic dosage …
mechanisms aiming to enhance the antineoplastic effect, decrease the therapeutic dosage …
Evaluation of the therapeutic potential of masitinib and expression of its specific targets c‐Kit, PDGFR‐α, PDGFR‐β, and Lyn in canine prostate cancer cell lines
K Klose, EM Packeiser… - Veterinary and …, 2022 - Wiley Online Library
Canine prostate cancer is classified into adenocarcinoma, transitional cell carcinoma with
prostatic involvement, and mixed forms. Early metastatic spread leads to poor prognosis and …
prostatic involvement, and mixed forms. Early metastatic spread leads to poor prognosis and …
Comparative pathobiology of canine and human prostate cancer: state of the art and future directions
Simple Summary Prostate cancer (PC) is one of the main types of cancer that affects the
male population worldwide. In recent decades, there has been a significant evolution in the …
male population worldwide. In recent decades, there has been a significant evolution in the …
Ablation of red stable transfected claudin expressing canine prostate adenocarcinoma and transitional cell carcinoma cell lines by C-CPE gold-nanoparticle-mediated …
S Alnajjar, I Nolte, A Becker, JT Schille… - International journal of …, 2021 - mdpi.com
Claudin (CLDN) proteins are commonly expressed in cancers and targeted in novel
therapeutic approaches. The C-terminal of Clostridium perfringens enterotoxin (C-CPE) …
therapeutic approaches. The C-terminal of Clostridium perfringens enterotoxin (C-CPE) …
RNA-seq of nine canine prostate cancer cell lines reveals diverse therapeutic target signatures
EM Packeiser, L Taher, W Kong, M Ernst, J Beck… - Cancer cell …, 2022 - Springer
Background Canine prostate adenocarcinoma (PAC) and transitional cell carcinoma (TCC)
are typically characterized by metastasis and chemoresistance. Cell lines are important …
are typically characterized by metastasis and chemoresistance. Cell lines are important …
Establishment and characterization of urothelial carcinoma cell lines with and without BRAF mutation (V595E) in dogs
H Yamasaki, Y Uematsu, K Okano, M Ichikawa… - In Vitro Cellular & …, 2022 - Springer
Each 5 urothelial carcinoma (UC) cell lines with and without the v-Raf murine sarcoma virus
oncogene homolog B (BRAF) gene mutation (V595E) were established and examined …
oncogene homolog B (BRAF) gene mutation (V595E) were established and examined …