RNA-based therapies have catalyzed a revolutionary transformation in the biomedical
landscape, offering unprecedented potential in disease prevention and treatment. However …

RNA modifications, known as the “epitranscriptome”, represent a key layer of regulation that
influences a wide array of biological processes in mesenchymal stem cells (MSCs). These …

N 4-Acetylcytidine (ac4C) has been found to affect a variety of cellular and biological
processes. For a mechanistic understanding of the roles of ac4C in biology and disease, we …

As epigenetic modifications, lactylation and N6-methyladenosine (m6A) have attracted wide
attention. Arsenite is an environmental pollutant that has been proven to induce idiopathic …

An immunosuppressive state is a typical feature of the tumor microenvironment. Despite the
dramatic success of immune checkpoint inhibitor (ICI) therapy in preventing tumor cell …

The oldest known highly conserved modification of RNA, N4-acetylcytidine, is widely
distributed from archaea to eukaryotes and acts as a posttranscriptional chemical …

RNA methylation, an epigenetic modification that does not alter gene sequence, may be
important to diverse biological processes. Protein regulators of RNA methylation include …

With recent advancements in biological research, long non-coding RNAs (lncRNAs) with
lengths exceeding 200 nucleotides have emerged as pivotal regulators of gene expression …

It is apparent that various functional units within the cellular machinery are derived from
RNAs. The evolution of sequencing techniques has resulted in significant insights into …

Long non-coding RNAs (lncRNAs) are emerging as a major class of gene products that
have central roles in cell and developmental biology. Natural antisense transcripts (NATs) …