Xerostomia induced by radiotherapy: an overview of the physiopathology, clinical evidence, and management of the oral damage

R Pinna, G Campus, E Cumbo, I Mura… - … and clinical risk …, 2015 - Taylor & Francis
Background The irradiation of head and neck cancer (HNC) often causes damage to the
salivary glands. The resulting salivary gland hypofunction and xerostomia seriously reduce …

A systematic review of quality of life in head and neck cancer treated with surgery with or without adjuvant treatment

S Rathod, J Livergant, J Klein, I Witterick, J Ringash - Oral oncology, 2015 - Elsevier
Quality of life (QoL) is an important consideration in the management of head and neck
cancers (HNC). We systematically reviewed the literature to assess the impact of curative …

A 12 country field study of the EORTC QLQ-C30 (version 3.0) and the head and neck cancer specific module (EORTC QLQ-H&N35) in head and neck patients

K Bjordal, A De Graeff, PM Fayers, E Hammerlid… - European journal of …, 2000 - Elsevier
This study tests the reliability and validity of the European Organization for Research and
Treatment of Cancer (EORTC) head and neck cancer module (QLQ-H&N35) and version 3.0 …

Health-related quality of life in long-term head and neck cancer survivors: a comparison with general population norms

E Hammerlid, C Taft - British journal of cancer, 2001 - nature.com
To examine the health-related quality of life (HRQL) in long-term head and neck (H&N)
cancer survivors compared with general population norms. HRQL was assessed with three …

Long‐term quality of life of patients with head and neck cancer

A de Graeff, JRJ de Leeuw, WJG Ros… - The …, 2000 - Wiley Online Library
Objectives: To describe prospectively the long‐term changes of quality of life and mood in
patients with squamous cell carcinoma of the head and neck treated with surgery and/or …

Health-related quality of life in oral cancer: a review

A Chandu, ACH Smith, SN Rogers - Journal of oral and maxillofacial …, 2006 - Elsevier
PURPOSE: Health-related quality of life (HRQOL) has now become an important outcome
measure in the assessment of patients treated for oral cancer. We summarize the influence …

Radiotherapy-related fatigue

BA Jereczek-Fossa, HR Marsiglia… - Critical reviews in oncology …, 2002 - Elsevier
Radiotherapy-induced fatigue is a common early and chronic side-effect of irradiation,
reported in up to 80 and 30% of patients during radiation therapy and at follow-up visits …

Qantitative dose-volume response analysis of changes in parotid gland function after radiotheraphy in the head-and-neck region

JM Roesink, MA Moerland, JJ Battermann… - International Journal of …, 2001 - Elsevier
Purpose: To study the radiation tolerance of the parotid glands as a function of dose and
volume irradiated. Methods and Materials: One hundred eight patients treated with primary …

A prospective study of quality of life in head and neck cancer patients. Part I: at diagnosis

E Hammerlid, K Bjordal, M Ahlner‐Elmqvist… - The …, 2001 - Wiley Online Library
Abstract Purpose A Swedish and Norwegian study was designed to examine health‐related
quality of life (HQL) in patients with head and neck cancer (head and neck) at diagnosis and …

Combined chemotherapy and radiation therapy for head and neck malignancies: quality of life issues

NP Nguyen, S Sallah, U Karlsson, JE Antoine - Cancer, 2002 - Wiley Online Library
BACKGROUND The standard of care for locally advanced head and neck carcinoma usually
has been surgery followed by radiation therapy. Patient survival using this approach has …