Stroke, the third leading cause of death and disability worldwide, is undergoing a change in
perspective with the emergence of new ideas on neurodegeneration. The concept that …

With more than 795,000 cases occurring every year, stroke has become a major problem in
the United States across all demographics. Stroke is the leading cause of long-term …

The immune response to ischemic stroke is an area of study that is at the forefront of stroke
research and presents promising new avenues for treatment development. Upon cerebral …

One of the leading causes of neurological mortality, disability, and dementia worldwide is
cerebral ischemia. Among the many pathological phenomena, the immune system plays an …

Ischemic stroke constitutes the major cause of death and disability in the industrialized
world. The interest in microglia arose from the evidence outlining the role of …

Background Lymphocyte-to-monocyte ratio (LMR) is associated with diverse malignancies
and cardiovascular diseases. However, it has not yet been identified whether LMR is …

We studied the expression of pro-and anti-inflammatory molecules in microglia and
infiltrating monocyte-derived macrophages after permanent Middle Cerebral Artery …

Regulatory T cells (Tregs) are known to protect against ischemic stroke. However, the low
frequency of Tregs restricts their clinical utility. This study investigated whether expanding …

Ischemic stroke is a leading cause of disability and mortality. Despite extensive efforts in
stroke research, the only pharmacological treatment currently available is arterial …

Inflammatory responses are accountable for secondary injury induced by acute ischemic
stroke (AIS). Previous studies indicated that O-GlcNAc modification (O-GlcNAcylation) is …