[HTML][HTML] Anti-double stranded DNA antibodies: origin, pathogenicity, and targeted therapies
X Wang, Y Xia - Frontiers in immunology, 2019 - frontiersin.org
Systemic lupus erythematosus (SLE) is characterized by high-titer serological
autoantibodies, including antibodies that bind to double-stranded DNA (dsDNA). The origin …
autoantibodies, including antibodies that bind to double-stranded DNA (dsDNA). The origin …
Regulatory T cells in SLE: biology and use in treatment
S Giang, A La Cava - Current rheumatology reports, 2016 - Springer
T regulatory cells (Tregs) represent a phenotypically and functionally heterogeneous group
of lymphocytes that exert immunosuppressive activities on effector immune responses …
of lymphocytes that exert immunosuppressive activities on effector immune responses …
Bone morphogenetic protein‐2 promotes osteosarcoma growth by promoting epithelial‐mesenchymal transition (EMT) through the Wnt/β‐catenin signaling pathway
H Tian, T Zhou, H Chen, C Li, Z Jiang… - Journal of …, 2019 - Wiley Online Library
The correlation between BMP‐2 and osteosarcoma growth has gained increased interest in
the recent years, however, there is still no consensus. In this study, we tested the effects of …
the recent years, however, there is still no consensus. In this study, we tested the effects of …
[HTML][HTML] Nanoparticles engineered as artificial antigen-presenting cells induce human CD4+ and CD8+ Tregs that are functional in humanized mice
S Giang, DA Horwitz, S Bickerton… - Frontiers in …, 2021 - frontiersin.org
Artificial antigen-presenting cells (aAPCs) are synthetic versions of naturally occurring
antigen-presenting cells (APCs) that, similar to natural APCs, promote efficient T effector cell …
antigen-presenting cells (APCs) that, similar to natural APCs, promote efficient T effector cell …
T cells in systemic lupus erythematosus
JL Paredes, R Fernandez-Ruiz… - Rheumatic Disease …, 2021 - rheumatic.theclinics.com
T cells have a central role in systemic lupus erythematosus (SLE) pathogenesis. T-cell
dysregulation affects peripheral tolerance and induces inappropriate activation of B cells. 1 …
dysregulation affects peripheral tolerance and induces inappropriate activation of B cells. 1 …
Tregs in SLE: an Update
A La Cava - Current rheumatology reports, 2018 - Springer
Abstract Purpose of Review There has been great interest in understanding why T
regulatory cells (Tregs) are reduced in number and/or in function in several autoimmune …
regulatory cells (Tregs) are reduced in number and/or in function in several autoimmune …
Novel approaches to the development of targeted therapeutic agents for systemic lupus erythematosus
Z Sthoeger, A Sharabi, E Mozes - Journal of autoimmunity, 2014 - Elsevier
Systemic lupus erythematosus (SLE) is a chronic multisystem disease in which various cell
types and immunological pathways are dysregulated. Current therapies for SLE are based …
types and immunological pathways are dysregulated. Current therapies for SLE are based …
Update on the treatment of lupus nephritis
J Hogan, GB Appel - Current opinion in nephrology and …, 2013 - journals.lww.com
Update on the treatment of lupus nephritis : Current Opinion in Nephrology and Hypertension
Update on the treatment of lupus nephritis : Current Opinion in Nephrology and Hypertension …
Update on the treatment of lupus nephritis : Current Opinion in Nephrology and Hypertension …
Peptide-based immunotherapy in lupus: Where are we now?
R P. Singh, D S. Bischoff, SS Singh… - Rheumatology and …, 2023 - degruyter.com
In autoimmune rheumatic diseases, immune hyperactivity and chronic inflammation
associate with immune dysregulation and the breakdown of immune self-tolerance. A …
associate with immune dysregulation and the breakdown of immune self-tolerance. A …