Personalizing mechanical ventilation according to physiologic parameters to stabilize alveoli and minimize ventilator induced lung injury (VILI)

GF Nieman, J Satalin, P Andrews, H Aiash… - Intensive care medicine …, 2017 - Springer
It has been shown that mechanical ventilation in patients with, or at high-risk for, the
development of acute respiratory distress syndrome (ARDS) can be a double-edged sword …

S3 Guideline Sepsis—prevention, diagnosis, therapy, and aftercare: long version

FM Brunkhorst, MA Weigand, M Pletz… - Medizinische Klinik …, 2020 - Springer
BeieinerSepsishandeltessichumeinelebens… Organdysfunktion ausgelöst durch eine
Infektion, die mit einer Regulationsstörung beim Wirt einhergeht. Ähnlich wie bei …

[PDF][PDF] S3-leitlinie sepsis–prävention, diagnose, therapie und nachsorge

FM Brunkhorst, MA Weigand, M Pletz… - 2020 - publications.goettingen-research …
BeieinerSepsishandeltessichumeinelebens… Organdysfunktion ausgelöst durch eine
Infektion, die mit einer Regulationsstörung beim Wirt einhergeht. Ähnlich wie bei …

Selecting the 'right'positive end-expiratory pressure level

L Gattinoni, E Carlesso, M Cressoni - Current opinion in critical …, 2015 - journals.lww.com
When compared, most of the methods give the same positive end-expiratory pressure
values in patients with higher and lower recruitability. The positive end-expiratory …

Mice deficient in the gene for cytochrome P450 (CYP) 1A1 are more susceptible than wild-type to hyperoxic lung injury: evidence for protective role of CYP1A1 against …

K Lingappan, W Jiang, L Wang, G Wang… - Toxicological …, 2014 - academic.oup.com
Hyperoxia contributes to acute lung injury in diseases such as acute respiratory distress
syndrome in adults and bronchopulmonary dysplasia in premature infants. Cytochrome …

Volume capnography in the intensive care unit: potential clinical applications

JW Kreit - Annals of the American Thoracic Society, 2019 - atsjournals.org
Volume capnography provides a noninvasive, continuous display of the fractional
concentration or partial pressure of carbon dioxide (Pco2) versus exhaled volume. Derived …

Role of cytochrome P450 (CYP) 1A in hyperoxic lung injury: analysis of the transcriptome and proteome

K Lingappan, S Maity, W Jiang, L Wang, X Couroucli… - Scientific reports, 2017 - nature.com
Hyperoxia contributes to lung injury in experimental animals and diseases such as acute
respiratory distress syndrome in humans. Cytochrome P450 (CYP) 1A enzymes are …

[HTML][HTML] The use of positive end expiratory pressure in patients affected by COVID-19: Time to reconsider the relation between morphology and physiology

G Perchiazzi, M Pellegrini, E Chiodaroli, I Urits… - Best Practice & …, 2020 - Elsevier
Coronavirus disease 2019 (COVID-19) is a new disease with different phases that can be
catastrophic for subpopulations of patients with cardiovascular and pulmonary disease …

A modified method to assess tidal recruitment by electrical impedance tomography

T Muders, B Hentze, P Simon, F Girrbach… - Journal of clinical …, 2019 - mdpi.com
Avoiding tidal recruitment and collapse during mechanical ventilation should reduce the risk
of lung injury. Electrical impedance tomography (EIT) enables detection of tidal recruitment …

Measurement of electrical impedance tomography-based regional ventilation delay for individualized titration of end-expiratory pressure

T Muders, B Hentze, S Kreyer, KH Wodack… - Journal of Clinical …, 2021 - mdpi.com
Rationale: Individualized positive end-expiratory pressure (PEEP) titration might be
beneficial in preventing tidal recruitment. To detect tidal recruitment by electrical impedance …