A new liquid metal ion gun (LMIG) filled with bismuth has been fitted to a time-of-flight—
secondary ion mass spectrometer (TOF-SIMS). This source provides beams of Bi nq+ …

Mass spectrometry imaging (MSI) has proven to be extremely useful for applications such as
the spatial analysis of peptides and proteins in biological tissue, the performance …

Sample preparation is one of the most crucial processes in proteomics research. The results
of the experiment depend on the condition of the starting material. Therefore, the proper …

Mass spectrometry imaging and profiling of individual cells and subcellular structures
provide unique analytical capabilities for biological and biomedical research, including …

Molecular imaging of tissue by MALDI mass spectrometry is a powerful tool for visualizing
the spatial distribution of constituent analytes with high molecular specificity. Although the …

Atmospheric pressure imaging mass spectrometry is a rapidly expanding field that offers
advantages in the ability to study biological systems in their native condition, simplified …

Matrix-assisted laser desorption/ionization mass spectrometry imaging (MALDI MSI) is a
label-free technique for identifying multiplex metabolites and determining both their …

Surface metallization by plasma coating enhances desorption/ionization of membrane
components such as lipids and sterols in imaging time-of-flight secondary ion mass …

This concise tutorial review provides a description of the current state of the art in the
application of time-of flight based secondary ion mass spectrometry (TOF-SIMS) in the field …

An atmospheric pressure (AP) MALDI imaging interface was developed for an orthogonal
acceleration time-of-flight mass spectrometer and utilized to analyze peptides …