Nanostructure-initiator mass spectrometry (NIMS) is a highly sensitive, matrix-free technique
that is well suited for biofluid analysis and imaging of biological tissues. Here we provide a …

Secondary ion mass spectrometry is commonly used to study many different types of
complex surfaces. Yet, compared with MALDI and ESI–MS, SIMS has not made a significant …

Time-of-flight secondary ion mass spectrometry (TOF-SIMS) has been used in imaging of
small molecules (< 500 Da) in fingerprints, such as gunshot residues and illicit drugs …

Matrix-enhanced secondary ion mass spectrometry (ME-SIMS) has overcome one of the
biggest disadvantages of SIMS analysis by providing the ability to detect intact biomolecules …

Recent developments in instrumentation, ion beams or analyzers, for cluster time‐of‐flight
secondary ion mass spectrometry (TOF‐SIMS) imaging are described here. The methods …

Matrix-assisted laser desorption/ionization (MALDI) is a new tool that can acquire the
localization of various compounds, including peptides and proteins, directly from tissue …

Class IA PI3Ks (phosphoinositide 3-kinases) consist of a p110 catalytic subunit bound to
one of five regulatory subunits, known as p85s. Under unstimulated conditions, p85 …

Small molecule metabolites (SMMs, typically< 500 Da) are important cellular constituents
closely associated with tumor development and progression. However, in situ label-free …

Proteomics, the large‐scale study of protein expression in organisms, offers the potential to
evaluate global changes in protein expression and their post‐translational modifications that …

In the dc voltage-applied electrohydrodynamic (EHD) jet printing of metal nanoparticles, the
residual charge of droplets deposited on a substrate changes the electrostatic field …