The intraocular lens contains high levels of both cholesterol and sphingolipids, which are
believed to be functionally important for normal lens physiology. The aim of this study was to …

MALDI mass spectrometers have become popular tools for imaging histological sections.
Currently this technology is primarily used for imaging naturally occurring molecules. Here …

We describe here the use of a hybrid ionization approach, matrix-enhanced surface-assisted
laser desorption/ionization mass spectrometry (ME-SALDI-MS) in bioimaging. ME-SALDI …

The capabilities of time-of-flight secondary ion mass spectrometry (TOF-SIMS) with regards
to limits in lateral resolution for biological samples are examined using supported lipid …

The eye is an elegant organ consisting of a number of tissues and fluids with specialised
functions that together allow it to effectively transmit and transduce light input to the brain for …

Imaging mass spectrometry technology is rapidly developing. New desorption and ionization
methods allow access to an increasingly large number of biomolecular systems. Sensitivity …

Investigation of the peptidome of the nervous system containing large, often easily
identifiable neurons has greatly benefited from single-cell matrix-assisted laser …

We demonstrate the use of gold nanoparticles (AuNPs) to enhance the secondary ion
emission of peptides in time-of-flight secondary ion mass spectrometry (TOF-SIMS). The …

Imaging mass spectrometry (IMS) technology utilizes MALDI MS to map molecules of
interest in thin tissue sections. In this study, we have evaluated the potential of MALDI IMS to …

Mass spectrometry imaging (MSI) of neuropeptides has become a well-established method
with the ability to combine spatially resolved information from immunohistochemistry with …