Extracellular vehicles (EVs) are a heterogeneous group of cell and membranous particles
originating from different cell compartments. EVs participate in many essential physiological …

Cardiovascular diseases (CVDs) are the leading cause of death worldwide. The initial stage
of CVDs is characterized by endothelial dysfunction, defined as the limited bioavailability of …

The ability of exosomes to transport different molecular cargoes and their ability to influence
various physiological factors is already well known. An exciting area of research explores …

Background This study aimed to evaluate the relationship between thyroid-related
hormones and vascular complications in type 2 diabetes mellitus (T2DM) patients with …

Background Perinatal hypoxia affects a lot of neonates worldwide every year, however its
effects on the functioning of systemic circulation are not clear yet. We aimed at investigation …

The activity of many vasomotor signaling pathways strongly depends on extracellular/
intracellular pH. Nitric oxide (NO) is one of the most important vasodilators produced by the …

The aim of the work was to explore the correlation between thyroid hormones and coronary
atherosclerotic severity. This cross-sectional study included 340 euthyroid patients who …

The gasotransmitters, nitric oxide (NO), hydrogen sulfide (H 2 S), and carbon monoxide
(CO), are endogenously-produced volatile molecules that perform signaling functions …

Recurrent spontaneous abortion (RSA) has various causes, including chromosomal
abnormalities, prethrombotic state, and abnormal uterine anatomical factors. However, the …

Peroxynitrite, a reactive nitrogen species, is one of the strongest oxidants in the body.
Depending on the conditions, it either undergoes biotransformation and detoxification or …