Strategic approaches to improvise peptide drugs as next generation therapeutics

P Barman, S Joshi, S Sharma, S Preet… - International journal of …, 2023 - Springer
In recent years, the occurrence of a wide variety of drug-resistant diseases has led to an
increase in interest in alternate therapies. Peptide-based drugs as an alternate therapy hold …

Methicillin Resistant Staphylococcus aureus: Molecular Mechanisms Underlying Drug Resistance Development and Novel Strategies to Combat

AA Abebe, AG Birhanu - Infection and Drug Resistance, 2023 - Taylor & Francis
Antimicrobial resistance (AMR) represents a major threat to global health. Infection caused
by Methicillin-resistant Staphylococcus aureus (MRSA) is one of the well-recognized global …

[HTML][HTML] Bactericidal effect of Cecropin A fused endolysin on drug-resistant gram-negative pathogens

J Lim, J Hong, Y Jung, J Ha, H Kim… - … of Microbiology and …, 2022 - ncbi.nlm.nih.gov
The rapid spread of superbugs leads to the escalation of infectious diseases, which
threatens public health. Endolysins derived from bacteriophages are spotlighted as …

The problems and prospects of developing food products from high-protein raw materials

E Bychkova, L Rozhdestvenskaya, E Podgorbunskikh… - Food Bioscience, 2023 - Elsevier
The world community is witnessing global changes to the food system. There has been a
steady trend in protein consumption toward replacing animal-derived protein with plant …

Anti-Pseudomonas aeruginosa activity of natural antimicrobial peptides when used alone or in combination with antibiotics

X Chen, S Su, Y Yan, L Yin, L Liu - Frontiers in Microbiology, 2023 - frontiersin.org
The World Health Organization has recently published a list of 12 drug-resistant bacteria that
posed a significant threat to human health, and Pseudomonas aeruginosa (P. aeruginosa) …

Virulence factors, antimicrobial resistance and phylogeny of bovine mastitis-associated Streptococcus dysgalactiae

BL Crippa, MX Rodrigues, T Tomazi, Y Yang… - Journal of Dairy …, 2023 - cambridge.org
We carried out a thorough genetic evaluation of Streptococcus dysgalactiae isolated from
clinical bovine mastitis cases and performed a phylogenetic analysis to represent the …

Progress and future of the computational design of antimicrobial peptides (AMPs): bio-inspired functional molecules

M Nedyalkova, AS Paluch, DP Vecini, M Lattuada - Digital Discovery, 2024 - pubs.rsc.org
The effectiveness of antibiotics is greatly enhanced by their ability to target invasive
organisms involved in the ancient evolutionary battle between hosts and pathogens …

A Review of the Important Weapons against Antimicrobial Resistance in Sub-Saharan Africa

N Gahamanyi, T Umuhoza, SI Saeed, LN Mayigane… - Applied …, 2023 - mdpi.com
Antimicrobial resistance (AMR) is one of the top 10 global health threats facing humanity,
and the sub-Saharan Africa (SSA) is among the heavily affected regions due to its weak …

[HTML][HTML] A novel endogenous antimicrobial peptide MP-4 derived from koumiss of Inner Mongolia by peptidomics, and effects on Staphylococcus aureus

M Zhang, S Li, J Zhao, Q Shuang, Y Xia, F Zhang - LWT, 2024 - Elsevier
Koumiss is known as a traditional milk-based beverage with high nutritional value and
antimicrobial potential. In this study, we investigated the antibacterial effects of koumiss …

Study on antimicrobial activity of sturgeon skin mucus polypeptides (Rational Design, Self-Assembly and Application)

B Yang, W Li, Y Mao, Y Zhao, Y Xue, X Xu, Y Zhao… - Food Chemistry: X, 2024 - Elsevier
Despite the favorable biocompatibility of natural antimicrobial peptides (AMPs), their scarcity
limits their practical application. Through rational design, the activity of AMPs can be …