Genetically modified pigs have become valuable tools for generating advances in animal
agriculture and human medicine. Importantly, in vitro production and manipulation of …

In vitro maturation (IVM) of human immature oocytes has been offered to women who are at
risk of developing ovarian hyperstimulation syndrome (OHSS) caused by gonadotropin …

Context: Polycystic ovary syndrome (PCOS), a major cause of anovulatory infertility, is
characterized by arrested follicular growth. Altered protein levels in the follicular fluid …

The ovarian stroma, the microenvironment in which female gametes grow and mature,
becomes inflamed and fibrotic with age. Hyaluronan is a major component of the ovarian …

Abstract 1 Hyaluronan (HA) is a non-sulfated gylcosaminglycan naturally occurring polymer
found in tissues and 2 fluids of mammals including the reproductive system. Its biosynthesis …

Hyaluronic acid (HA), an important component of the extracellular matrix, plays a crucial role
for cumulus cell expansion. Genes and proteins involved in HA synthesis and its receptor …

Copper (Cu) ions have redox activity and act as cofactors of enzymes related to respiration,
radical detoxification, and iron metabolism. In this study, we aimed to examine the effects of …

Perfluorooctane sulfonate (PFOS) is a broadly used man-made surfactant whose long half-
life has led to bioaccumulation. This perfluorinated compound is ubiquitous in human body …

To investigate the effects of tannins (TA) on porcine oocyte in vitro maturation (IVM), different
concentrations of TA (0, 1, 10 and 100 μg/mL) were supplemented with a maturation …

In ovarian follicles, cumulus cells communicate with the oocyte through gap junction
intercellular communication (GJIC), to nurture the oocyte and control its meiosis arrest and …