Acute-on-chronic liver failure (ACLF) is associated with increased short and long-term
mortality. Animal models of liver failure have demonstrated that granulocyte-colony …

Patients with acute-on-chronic liver failure (ACLF) have a devastating prognosis and
therapeutic options are limited. Granulocyte-colony stimulating factor (G-CSF) mobilizes …

Acetaminophen (APAP) is the main cause of acute liver failure in the West. Specific
efficacious therapies for acute liver failure (ALF) are limited and time-dependent. The …

Hepatitis C virus (HCV) infection in Tupaia belangeri (Tupaia) represents an important
model of HCV infection. Xanthohumol (XN), a major prenylated chalcone from hops, has …

Background Acute‐on‐chronic liver failure (ACLF) is a clinically and pathophysiologically
distinct condition from acutely decompensated cirrhosis and is characterised by systemic …

Abstract Background & Aims Acute liver failure (ALF) is a life‐threatening condition with a
high mortality rate. The expression of urokinase plasminogen activator receptor (uPAR …

Background: Acute-on-chronic liver failure (ACLF) mostly occurs when there is an acute
insult to the liver in patients with pre-existing liver disease, and it is characterized by a high …

Advancements in rheumatoid arthritis (RA) treatment protocols and introduction of targeted
biological therapies have markedly improved patient outcomes, despite this, up to 50% of …

急性肝衰竭是一种严重而复杂的肝脏疾病, 短期病死率高, 其发病机制尚未明确,
亦缺乏特效药物. 动物模型制备对于深层次揭露急性肝衰竭发病和药物疗效机制具有重要意义 …

Protective effects of granulocyte colony stimulating factor (G-CSF) in acute liver injury via
marrow cell mobilization have been reported in several studies. But exact mode of action …