The ecology and evolution of microbial competition

M Ghoul, S Mitri - Trends in microbiology, 2016 - cell.com
Microbes are typically surrounded by different strains and species with whom they compete
for scarce nutrients and limited space. Given such challenging living conditions, microbes …

Natural product discovery: past, present, and future

L Katz, RH Baltz - Journal of Industrial Microbiology and …, 2016 - academic.oup.com
Microorganisms have provided abundant sources of natural products which have been
developed as commercial products for human medicine, animal health, and plant crop …

Actinomycetes: still a source of novel antibiotics

O Genilloud - Natural product reports, 2017 - pubs.rsc.org
Covering: 2006 to 2017 Actinomycetes have been, for decades, one of the most important
sources for the discovery of new antibiotics with an important number of drugs and analogs …

Genome mining methods to discover bioactive natural products

KD Bauman, KS Butler, BS Moore… - Natural Product …, 2021 - pubs.rsc.org
Covering: 2016 to 2021 With genetic information available for hundreds of thousands of
organisms in publicly accessible databases, scientists have an unprecedented opportunity …

Discovery of microbial natural products by activation of silent biosynthetic gene clusters

PJ Rutledge, GL Challis - Nature reviews microbiology, 2015 - nature.com
Microorganisms produce a wealth of structurally diverse specialized metabolites with a
remarkable range of biological activities and a wide variety of applications in medicine and …

Degradable carbon dots with broad-spectrum antibacterial activity

H Li, J Huang, Y Song, M Zhang, H Wang… - … applied materials & …, 2018 - ACS Publications
The infection of bacteria and fungus is one of the most challenging global threats to human
health. With the recent advancement in nanoscience and nanotechnology, much progress …

Chemical ecology of antibiotic production by actinomycetes

A Van der Meij, SF Worsley… - FEMS microbiology …, 2017 - academic.oup.com
Actinomycetes are a diverse family of filamentous bacteria that produce a plethora of natural
products relevant for agriculture, biotechnology and medicine, including the majority of the …

Insights into secondary metabolism from a global analysis of prokaryotic biosynthetic gene clusters

P Cimermancic, MH Medema, J Claesen, K Kurita… - Cell, 2014 - cell.com
Although biosynthetic gene clusters (BGCs) have been discovered for hundreds of bacterial
metabolites, our knowledge of their diversity remains limited. Here, we used a novel …

Natural products: a continuing source of novel drug leads

GM Cragg, DJ Newman - Biochimica et Biophysica Acta (BBA)-General …, 2013 - Elsevier
BACKGROUND: Nature has been a source of medicinal products for millennia, with many
useful drugs developed from plant sources. Following discovery of the penicillins, drug …

[HTML][HTML] Multifunctional role of Actinobacteria in agricultural production sustainability: A review

K Boubekri, A Soumare, I Mardad, K Lyamlouli… - Microbiological …, 2022 - Elsevier
The growing interest in low-input agriculture in recent years has focused the use of microbial
biofertilizers to improve plant growth and yield through a better mobilization of indigenous …