Extracellular vesicles are released by the majority of cell types and circulate in body fluids.
They function as a long-distance cell-to-cell communication mechanism that modulates the …

Mesenchymal stem cells (MSCs), as the most common cell source for stem cell therapy, play
an important role in the modulation of innate and adaptive immune responses and have …

Background: Mesenchymal stem cell (MSC)-derived exosomes are well recognized
immunomodulating agents for cardiac repair, while the detailed mechanisms remain elusive …

Mesenchymal stem cells (MSCs) are adult stromal cells that reside in virtually all postnatal
tissues. Due to their regenerative and immunomodulatory capacities, MSCs have attracted …

Acute kidney injury (AKI) and chronic kidney disease (CKD) are rising in global prevalence
and cause significant morbidity for patients. Current treatments are limited to slowing instead …

With the ever-increasing burden of kidney disease, the need for developing new
therapeutics to manage this disease has never been greater. Extracellular vesicles (EVs) …

Fibrosis is the unrelenting deposition of excessively large amounts of insoluble interstitial
collagen due to profound matrigenic activities of wound-associated myofibroblasts during …

Kidney diseases pose a threat to human health due to their rising incidence and fatality rate.
In preclinical and clinical studies, it has been acknowledged that mesenchymal stem cells …

Currently available therapies for rheumatoid arthritis (RA) are inadequate to alleviate the
inflammation and reduce joint damage. While the immune-regulatory effect of human …

Kidney disease (KD) is a life-threatening disease characterized by high morbidity and
mortality in clinical settings, which can be caused by many reasons, and the incidence …