Alzheimer's disease (AD) is the most common cause of dementia and is currently one of the
biggest public health concerns in the world. Mitochondrial dysfunction in neurons is one of …

MicroRNAs are post-transcriptional regulators of gene expression, crucial for neuronal
differentiation, survival, and activity. Age-related dysregulation of microRNA biogenesis …

Epigenetics is a quickly growing field encompassing mechanisms regulating gene
expression that do not involve changes in the genotype. Epigenetics is of increasing …

Prion diseases are transmissible neurodegenerative disorders affecting both humans and
animals. The cellular prion protein, PrP C, and the abnormal infectious form, PrP Sc, are …

Neurodegenerative diseases originate from neuronal loss in the central nervous system
(CNS). These debilitating diseases progress with age and have become common due to an …

Huntington's disease (HD) is a progressive neurodegenerative disorder caused by a
trinucleotide repeat expansion in the huntingtin (HTT) gene, which is expressed ubiquitously …

Alzheimer's disease (AD) and related tauopathies comprise a large group of
neurodegenerative diseases associated with the pathological aggregation of tau protein …

Aging constitutes the main risk factor for the development of neurodegenerative diseases.
This represents a major health issue worldwide that is only expected to escalate due to the …

MicroRNAs (miRNAs) are essential post-transcriptional gene regulators involved in various
neuronal and non-neuronal cell functions and play a key role in pathological conditions …

During the last two decades, microRNAs (miRNAs) emerged as critical regulators of gene
expression. By modulating the expression of numerous target mRNAs mainly at the post …