Overview of oral cavity squamous cell carcinoma: Risk factors, mechanisms, and diagnostics

A Chamoli, AS Gosavi, UP Shirwadkar, KV Wangdale… - Oral oncology, 2021 - Elsevier
Oral cavity squamous cell carcinoma (OCSCC) is the most common malignancy of the oral
cavity. The substantial risk factors for OCSCC are the consumption of tobacco products …

Saliva and oral diseases

E Martina, A Campanati, F Diotallevi… - Journal of clinical …, 2020 - mdpi.com
Saliva is a fascinating biological fluid which has all the features of a perfect diagnostic tool.
In fact, its collection is rapid, simple, and noninvasive. Thanks to several transport …

RNA-based liquid biopsy in head and neck cancer

J Kabzinski, A Kucharska-Lusina, I Majsterek - Cells, 2023 - mdpi.com
Head and neck cancer (HNC) is a prevalent and diverse group of malignancies with
substantial morbidity and mortality rates. Early detection and monitoring of HNC are crucial …

Ganoderma lucidum polysaccharides inhibit in vitro tumorigenesis, cancer stem cell properties and epithelial-mesenchymal transition in oral squamous cell carcinoma

MR de Camargo, TF Frazon, KK Inacio… - Journal of …, 2022 - Elsevier
Ethnopharmacological relevance The polysaccharides of the millenary mushroom
Ganoderma lucidum (GL) have been shown for decades to present anti-tumor activities, but …

Implications of oral dysbiosis and HPV infection in head and neck cancer: from molecular and cellular mechanisms to early diagnosis and therapy

M Constantin, MC Chifiriuc, G Mihaescu… - Frontiers in …, 2023 - frontiersin.org
Head and neck cancer (HNC) is the sixth most common type of cancer, with more than half a
million new cases annually. This review focuses on the role of oral dysbiosis and HPV …

Malignant transformation rate of oral leukoplakia in the past 20 years: A systematic review and meta‐analysis

JY Guan, YH Luo, YY Lin, ZY Wu, JY Ye… - Journal of Oral …, 2023 - Wiley Online Library
Background This meta‐analysis aimed to assess the rate of malignant transformation (MT) of
oral leukoplakia (OL) and to study potential risk factors for the MT of OL into oral squamous …

Shooting at moving and hidden targets—tumour cell plasticity and the notch signalling pathway in head and neck squamous cell carcinomas

J Kałafut, A Czerwonka, A Anameriç… - Cancers, 2021 - mdpi.com
Simple Summary Cancers in the head and neck region are often aggressive and poorly
respond to both irradiation or chemotherapy. Chemotherapy is currently limited by a small …

Advantages of the combinatorial molecular targeted therapy of head and neck cancer—A step before anakoinosis-based personalized treatment

R Kleszcz - Cancers, 2023 - mdpi.com
Simple Summary Head and Neck Squamous Cell Carcinoma (HNSCC) is a major threat to
public health around the world. Its occurrence is linked to genetic events and environmental …

Current status of human papillomavirus-related head and neck cancer: from viral genome to patient care

H Dong, X Shu, Q Xu, C Zhu, AM Kaufmann, ZM Zheng… - Virologica Sinica, 2021 - Springer
Human papillomavirus (HPV) infection identified as a definitive human carcinogen is
increasingly being recognized for its role in carcinogenesis of human cancers. Up to 38 …

High risk-human papillomavirus in HNSCC: Present and future challenges for epigenetic therapies

L Ghiani, S Chiocca - International Journal of Molecular Sciences, 2022 - mdpi.com
Head and Neck Squamous Cell Carcinoma (HNSCC) is a highly heterogeneous group of
tumors characterized by an incidence of 650,000 new cases and 350,000 deaths per year …