Hepatitis C virus (HCV) entry is among the best-studied uptake processes for human
pathogenic viruses. Uptake follows a spatially and temporally tightly controlled program …

Cell-to-cell communication by exosomes controls normal and pathogenic processes,.
Viruses can spread in exosomes and thereby avoid immune recognition. While biogenesis …

Biomimetic cubic phases can be used for protein encapsulation in a variety of applications
such as biosensors and drug delivery. Cubic phases with a high concentration of cholesterol …

Membrane fusion, one of the most essential processes in the life of eukaryotes, occurs when
two separate lipid bilayers merge into a continuous bilayer and internal contents of two …

Cellular membranes are essential components of all living organisms. They are composed
of a complex mixture of lipids with diverse chemical structures and crucial biological …

Membrane fusion plays a lead role in the transport of vesicles, neurotransmission,
mitochondrial dynamics, and viral infection. There are fusion proteins that catalyze and …

Metabolic syndrome (MetS) refers to a cluster of metabolic dysregulations, which include
insulin resistance, obesity, atherogenic dyslipidemia and hypertension. The complex …

Nature has inspired the development of biomimetic membrane sensors in which the
functionalities of biological molecules, such as proteins and lipids, are harnessed for …

Interferon-induced transmembrane protein 3 (IFITM3) inhibits the entry of numerous viruses
through undefined molecular mechanisms. IFITM3 localizes in the endosomal-lysosomal …

We present a general strategy for determining the cholesterol-binding site of eukaryotic
membrane proteins in native-like lipid membranes by NMR spectroscopy. The strategy …