14-3-3 epsilon is an intracellular component of TNFR2 receptor complex and its activation protects against osteoarthritis
W Fu, A Hettinghouse, Y Chen, W Hu, X Ding… - Annals of the …, 2021 - ard.bmj.com
Objectives Osteoarthritis (OA) is the most common joint disease; however, the indeterminate
nature of mechanisms by which OA develops has restrained advancement of therapeutic …
nature of mechanisms by which OA develops has restrained advancement of therapeutic …
RNA-seq characterization of histamine-releasing mast cells as potential therapeutic target of osteoarthritis
Objective Mast cells in the osteoarthritis (OA) synovium correlate with disease severity. This
study aimed to further elucidate the role of mast cells in OA by RNA-Seq analysis and …
study aimed to further elucidate the role of mast cells in OA by RNA-Seq analysis and …
[HTML][HTML] The inhibitory receptor Siglec-8 interacts with FcεRI and globally inhibits intracellular signaling in primary mast cells upon activation
W Korver, A Wong, S Gebremeskel, GL Negri… - Frontiers in …, 2022 - frontiersin.org
Immunomodulation of mast cell (MC) activity is warranted in allergic and inflammatory
diseases where MCs have a central role in pathogenesis. Targeting Siglec-8, an inhibitory …
diseases where MCs have a central role in pathogenesis. Targeting Siglec-8, an inhibitory …
Increased risk of osteoarthritis in patients with atopic disease
Objectives To determine the incidence of osteoarthrits (OA) in patients with atopic disease
compared with matched non-exposed patients. Methods We conducted a retrospective …
compared with matched non-exposed patients. Methods We conducted a retrospective …
[HTML][HTML] The Corpus Adiposum Infrapatellare (Hoffa's Fat Pad)—the role of the infrapatellar fat pad in osteoarthritis pathogenesis
S Braun, F Zaucke, M Brenneis, AE Rapp, P Pollinger… - Biomedicines, 2022 - mdpi.com
In recent years, the infrapatellar fat pad (IFP) has gained increasing research interest. The
contribution of the IFP to the development and progression of knee osteoarthritis (OA) …
contribution of the IFP to the development and progression of knee osteoarthritis (OA) …
Smoking and tetramer tryptase accelerate intervertebral disc degeneration by inducing METTL14-mediated DIXDC1 m6 modification
Although cigarette smoking (CS) and low back pain (LBP) are common worldwide, their
correlations and the mechanisms of action remain unclear. We have shown that excessive …
correlations and the mechanisms of action remain unclear. We have shown that excessive …
The role of extracellular vesicles in osteoarthritis treatment via microenvironment regulation
H Yin, M Li, G Tian, Y Ma, C Ning, Z Yan, J Wu… - Biomaterials …, 2022 - spj.science.org
Osteoarthritis (OA) is a degenerative joint disease that is common among the middle-aged
and older populations, causes patients to experience recurrent pain in their joints and …
and older populations, causes patients to experience recurrent pain in their joints and …
Tick bites, IgE to galactose‐alpha‐1, 3‐galactose and urticarial or anaphylactic reactions to mammalian meat: The alpha‐gal syndrome
JM Wilson, L Erickson, M Levin, SM Ailsworth… - Allergy, 2024 - Wiley Online Library
The recent recognition of a syndrome of tick‐acquired mammalian meat allergy has
transformed the previously held view that mammalian meat is an uncommon allergen. The …
transformed the previously held view that mammalian meat is an uncommon allergen. The …
[HTML][HTML] GEO 数据库联合机器学习策略识别骨关节炎特征性lncRNA 分子标志物及实验验证
巧周, 健刘, 凌忻, 妍妍方, 亚军齐… - Journal of Sichuan …, 2023 - ncbi.nlm.nih.gov
GEO数据库联合机器学习策略识别骨关节炎特征性lncRNA分子标志物及实验验证- PMC Back to
Top Skip to main content NIH NLM Logo Access keys NCBI Homepage MyNCBI Homepage Main …
Top Skip to main content NIH NLM Logo Access keys NCBI Homepage MyNCBI Homepage Main …
[HTML][HTML] The immune role of the intestinal microbiome in knee osteoarthritis: a review of the possible mechanisms and therapies
C Sun, X Zhou, T Guo, J Meng - Frontiers in Immunology, 2023 - frontiersin.org
Osteoarthritis (OA) is a chronic degenerative joint disease characterized by cartilage
damage and synovial inflammation and carries an enormous public health and economic …
damage and synovial inflammation and carries an enormous public health and economic …