[HTML][HTML] The female vaginal microbiome in health and bacterial vaginosis

X Chen, Y Lu, T Chen, R Li - Frontiers in cellular and infection …, 2021 - frontiersin.org
The vaginal microbiome is an intricate and dynamic microecosystem that constantly
undergoes fluctuations during the female menstrual cycle and the woman's entire life. A …

Biofilm of Candida albicans: formation, regulation and resistance

R Pereira, RO Dos Santos Fontenelle… - Journal of Applied …, 2021 - academic.oup.com
Candida albicans is the most common human fungal pathogen, causing infections that
range from mucous membranes to systemic infections. The present article provides an …

[HTML][HTML] Antifungal drug-resistance mechanisms in Candida biofilms

J Kaur, CJ Nobile - Current opinion in microbiology, 2023 - Elsevier
Highlights•Few classes of antifungal drugs currently exist to treat fungal infections.•Infections
caused by Candida biofilms can be resistant to known antifungal drugs.•Growth in the …

Development and regulation of single- and multi-species Candida albicans biofilms

MB Lohse, M Gulati, AD Johnson… - Nature Reviews …, 2018 - nature.com
Candida albicans is among the most prevalent fungal species of the human microbiota and
asymptomatically colonizes healthy individuals. However, it is also an opportunistic …

[HTML][HTML] Mechanistic understanding of Candida albicans biofilm formation and approaches for its inhibition

T Atriwal, K Azeem, FM Husain, A Hussain… - Frontiers in …, 2021 - frontiersin.org
In recent years, the demand for novel antifungal therapies has increased several-folds due
to its potential to treat severe biofilm-associated infections. Biofilms are made by the sessile …

Forgotten fungi—the gut mycobiome in human health and disease

CE Huseyin, PW O'Toole, PD Cotter… - FEMS Microbiology …, 2017 - academic.oup.com
The human body is home to a complex and diverse microbial ecosystem that plays a central
role in host health. This includes a diversity of fungal species that is collectively referred to …

Pathogenesis and Clinical Relevance of Candida Biofilms in Vulvovaginal Candidiasis

C Rodríguez-Cerdeira, E Martínez-Herrera… - Frontiers in …, 2020 - frontiersin.org
The ability of Candida spp. to form biofilms is crucial for its pathogenicity, and thus, it should
be considered an important virulence factor in vulvovaginal candidiasis (VVC) and recurrent …

Candida Species Biofilms' Antifungal Resistance

S Silva, CF Rodrigues, D Araújo, ME Rodrigues… - Journal of Fungi, 2017 - mdpi.com
Candida infections (candidiasis) are the most prevalent opportunistic fungal infection on
humans and, as such, a major public health problem. In recent decades, candidiasis has …

Cationic chitosan derivatives as potential antifungals: A review of structural optimization and applications

Y Qin, P Li, Z Guo - Carbohydrate polymers, 2020 - Elsevier
The increasing resistance of pathogen fungi poses a global public concern. There are
several limitations in current antifungals, including few available fungicides, severe toxicity …

Antifungals discovery: an insight into new strategies to combat antifungal resistance

AM Fuentefria, B Pippi, DF Dalla Lana… - Letters in applied …, 2018 - academic.oup.com
Undeniably, new antifungal treatments are necessary against pathogenic fungi. Fungal
infections have significantly increased in recent decades, being highlighted as important …