Early detection of cancer
Survival improves when cancer is detected early. However,~ 50% of cancers are at an
advanced stage when diagnosed. Early detection of cancer or precancerous change allows …
advanced stage when diagnosed. Early detection of cancer or precancerous change allows …
Cancer models in preclinical research: A chronicle review of advancement in effective cancer research
H Sajjad, S Imtiaz, T Noor, YH Siddiqui… - Animal Models and …, 2021 - Wiley Online Library
Cancer is a major stress for public well‐being and is the most dreadful disease. The models
used in the discovery of cancer treatment are continuously changing and extending toward …
used in the discovery of cancer treatment are continuously changing and extending toward …
Hydrogels to engineer tumor microenvironments in vitro
In recent years, hydrogel-based three-dimensional tumor models have become increasingly
mainstream for cancer research. Hydrogels enable recapitulation of biochemical and …
mainstream for cancer research. Hydrogels enable recapitulation of biochemical and …
Synthetic matrix scaffolds engineer the in vivo tumor immune microenvironment for immunotherapy screening
Immunotherapy has emerged as one of the most powerful anti‐cancer therapies but is
stymied by the limits of existing preclinical models with respect to disease latency and …
stymied by the limits of existing preclinical models with respect to disease latency and …
Advances in 3D bioprinting for the biofabrication of tumor models
MG Sánchez-Salazar, MM Álvarez… - Bioprinting, 2021 - Elsevier
Cancer research depends on the challenging task of producing representative and reliable
models of human disease; these have largely been limited to mouse models or human …
models of human disease; these have largely been limited to mouse models or human …
[HTML][HTML] Patient-derived organoid analysis of drug resistance in precision medicine: is there a value?
A Abugomaa, M Elbadawy - Expert Review of Precision Medicine …, 2020 - Taylor & Francis
Cancer is the main health problem with high morbidity and mortality. The worldwide annual
incidence and deaths from cancers are estimated in millions [1, 2]. Hence, cancer therapy …
incidence and deaths from cancers are estimated in millions [1, 2]. Hence, cancer therapy …
[HTML][HTML] In vitro cancer models: a closer look at limitations on translation
In vitro cancer models are envisioned as high-throughput screening platforms for potential
new therapeutic discovery and/or validation. They also serve as tools to achieve …
new therapeutic discovery and/or validation. They also serve as tools to achieve …
[HTML][HTML] Conditional Cell Reprogramming and Air–Liquid Interface Modeling Life Cycle of Oncogenic Viruses (HPV and EBV) in Epithelial Cells and Virus-Associated …
AQ Rani, D Nurmemet, J Liffick, A Khan, D Mitchell, J Li… - Viruses, 2023 - mdpi.com
Several oncogenic viruses are associated with approximately 20% of human cancers.
Experimental models are crucial for studying the pathogenicity and biological aspects of …
Experimental models are crucial for studying the pathogenicity and biological aspects of …
[HTML][HTML] Playing on the dark side: SMYD3 acts as a cancer genome keeper in gastrointestinal malignancies
P Sanese, C Fasano, C Simone - Cancers, 2021 - mdpi.com
Simple Summary The activity of SMYD3 in promoting carcinogenesis is currently under
debate. Growing evidence seems to confirm that SMYD3 overexpression correlates with …
debate. Growing evidence seems to confirm that SMYD3 overexpression correlates with …
[PDF][PDF] Can computers conceive the complexity of cancer to cure it? Using artificial intelligence technology in cancer modelling and drug discovery
RC Adams, B Rashidieh - Mathematical Biosciences and …, 2020 - researchgate.net
Drug discovery and the development of safe and effective therapeutics is an intricate
procedure, further complicated in the context of cancer research by the inherent …
procedure, further complicated in the context of cancer research by the inherent …