Two well characterized signal transduction cascades regulating fungal development and
virulence are the MAP kinase and cAMP signaling cascades. Here we review the current …

▪ Abstract Cryptococcus neoformans is a pathogenic fungus that primarily afflicts
immunocompromised patients, infecting the central nervous system to cause …

Pulmonary infections due to Aspergillus fumigatus result from the development of a colony of
tightly associated hyphae in contact with the air, either in the alveoli (invasive aspergillosis) …

Melanin is an antioxidant polyphenol pigment required for the pathogenicity of many fungal
pathogens, but comprehensive regulatory mechanisms remain unidentified. In this study, we …

Melanins are ubiquitous complex polymers that are commonly known in humans to cause
pigmentation of our skin. Melanins are also present in bacteria, fungi, and helminths. In this …

Cryptococcus neoformans, an encapsulated fungal pathogen, causes meningoencephalitis
in immunocompromised patients. Recent in vivo studies have demonstrated that C …

The origin of virulence in environmental fungi that have no requirement for animal hosts in
their life cycle is enigmatic. Cryptococcus neoformans is a human pathogenic fungus with …

Virulence is the outcome of an interaction between the host and a microbe and is
characterized by a large array of opposing reactions operating at the host-pathogen …

Diversity of the Cryptococcus neoformans-Cryptococcus gattii species complex Page 1
Diversity of the Cryptococcus neoformans-Cryptococcus gattii species complex Marjan …

A protective role for antibodies has not previously been described for host defense against
the pathogenic fungus Histoplasma capsulatum (Hc). Mouse mAb's were generated from …