Melanin pigments are substances produced by a broad variety of pathogenic
microorganisms, including bacteria, fungi, and helminths. Microbes predominantly produce …

The human fungal pathogen Cryptococcus neoformans produces melanin in the presence of
various substrates, including the l enantiomer of 3, 4-dihydroxyphenylalanine (DOPA). The …

Melanin is a virulence factor for many pathogenic fungal species, including Cryptococcus
neoformans. Melanin is deposited in the cell wall, and melanin isolated from this fungus …

Infection with Cryptococcus neoformans begins when desiccated yeast cells or spores are
inhaled and lodge in the alveoli of the lungs. A subset of cryptococcal cells in the lungs …

Melanin is a natural pigment present in almost all biological groups, and is composed of
indolic polymers and characterized by black-brown colorization. Furthermore, it is one of the …

Melanins, or melanin-like compounds, may play a role in the pathogenesis of a number of
human fungal infections. This study investigated the production of melanin by the important …

Melanins are implicated in the pathogenesis of several human diseases, including some
microbial infections. In this study, we analyzed whether the conidia and the yeasts of the …

Melanins are enigmatic pigments produced by a wide variety of microorganisms including
bacteria and fungi. Here, we have isolated and characterized extracellular melanin from …

Passive immunization with monoclonal antibodies (MAbs) to melanin prolonged the survival
of and reduced the fungal burden in Cryptococcus neoformans-infected mice in comparison …

Almost all cells and organisms release membrane structures containing proteins, lipids, and
nucleic acids called extracellular vesicles (EVs), which have a wide range of functions …