High-fidelity DNA replication is critical for the faithful transmission of genetic information to
daughter cells. Following genotoxic stress, specialized DNA damage tolerance pathways …

Simple Summary Immunotherapy helps a person's immune system to target tumor cells.
Recent advances in cancer immunotherapy, including immune checkpoint inhibition …

Extracellular vesicles (EVs) are a group of nanoscale membrane-bound organelles
including exosomes, microvesicles (MVs), membrane particles, and apoptotic bodies, which …

The potential of immune checkpoint inhibitors (ICI) may be limited in situations where
immune cell fitness is impaired. Here, we show that the efficacy of cancer immunotherapies …

Gold nanoparticles (AuNPs) have received great attention for various medical applications
due to their unique physicochemical properties. AuNPs with tunable optical properties in the …

With an understanding of immunity in the tumor microenvironment, immunotherapy turns out
to be a powerful tool in the clinic to treat many cancers. The strategies applied in cancer …

Use of immunotherapy in recent years has revolutionized cancer treatment for certain types
of cancers. However, the broad utility of immunotherapy is limited because there are still …

Reinvigorating the antitumor immune response using immune checkpoint inhibitors (ICIs)
has revolutionized the treatment of several malignancies. However, extended use of ICIs …

The phenomenon of 'T cell exhaustion', a state of T cell dysfunction observed during chronic
infections and cancers, has been a major obstacle in mounting appropriate immune …

The interplay between microRNAs (miRNAs) and pluripotency transcription factors (TFs)
orchestrates the acquisition of cancer stem cell (CSC) features during the course of …