Abdominal aortic aneurysm: update on pathogenesis and medical treatments

J Golledge - Nature Reviews Cardiology, 2019 - nature.com
Abdominal aortic aneurysm (AAA) rupture is an important cause of death in adults. Currently,
the only treatment for AAA is open or endovascular surgical repair. In most parts of the …

Circulating markers of abdominal aortic aneurysm presence and progression

J Golledge, PS Tsao, RL Dalman, PE Norman - Circulation, 2008 - Am Heart Assoc
Given the potentially large number of markers that may have been investigated, we carried
out a staged search strategy. First, we performed a general search to identify biomarkers that …

Current status of medical management for abdominal aortic aneurysm

J Golledge, PE Norman - Atherosclerosis, 2011 - Elsevier
Previous trials indicate that surgical management of small abdominal aortic aneurysms
(AAA) does not reduce mortality. The medical management of AAA, however, has to a large …

Diagnosis and monitoring of abdominal aortic aneurysm: current status and future prospects

JV Moxon, A Parr, TI Emeto, P Walker… - Current problems in …, 2010 - Elsevier
Abdominal aortic aneurysm (AAA) remains an important cause of morbidity and mortality in
elderly men, and prevalence is predicted to increase in parallel with a global aging …

[HTML][HTML] Thrombus volume is associated with cardiovascular events and aneurysm growth in patients who have abdominal aortic aneurysms

A Parr, M McCann, B Bradshaw, A Shahzad… - Journal of vascular …, 2011 - Elsevier
BACKGROUND:: Patients with abdominal aortic aneurysms (AAA) are predisposed to
cardiovascular events and often experience continual expansion of their aneurysm …

Mouse models for abdominal aortic aneurysm

J Golledge, SM Krishna, Y Wang - British Journal of …, 2022 - Wiley Online Library
Abdominal aortic aneurysm (AAA) rupture is estimated to cause 200,000 deaths each year.
Currently, the only treatment for AAA is surgical repair; however, this is only indicated for …

Antithrombotic therapy in abdominal aortic aneurysm: beneficial or detrimental?

SJ Cameron, HM Russell… - Blood, The Journal of the …, 2018 - ashpublications.org
Abdominal aortic aneurysm (AAA) is a degenerative vascular pathology resulting in
significant morbidity and mortality in older adults due to rupture and sudden death. Despite …

Meta-analysis of peak wall stress in ruptured, symptomatic and intact abdominal aortic aneurysms

S Khosla, DR Morris, JV Moxon, PJ Walker… - Journal of British …, 2014 - academic.oup.com
Background Abdominal aortic aneurysm (AAA) is an important cause of sudden death;
however, there are currently incomplete means to predict the risk of AAA rupture. AAA peak …

Comparison of volume and diameter measurement in assessing small abdominal aortic aneurysm expansion examined using computed tomographic angiography

A Parr, C Jayaratne, P Buttner, J Golledge - European journal of radiology, 2011 - Elsevier
AIM: First we aimed to assess the reproducibility of a computer tomography angiography
(CTA) based technique for measuring infra-renal aortic volume and diameter. Second we …

Evaluation of the diagnostic and prognostic value of plasma D-dimer for abdominal aortic aneurysm

J Golledge, R Muller, P Clancy, M McCann… - European heart …, 2011 - academic.oup.com
Aims A number of biomarkers have been associated with abdominal aortic aneurysm (AAA),
but there has been no assessment of how such markers along with clinical risk factors can …