In the next two decades, the world is expected to see around 20 million cases of cancer.
Moreover, the types of cancer will vary considerably from country to other. Therefore, all …

The development and current status of the relationships between the structure of platinum
based anti-cancer drugs and their biological activities are reviewed. The early structure …

The crystal structures of the cyclobutanedicarboxylate (ebde) platinum (II) complexes of di-2-
pyridyl ketone (dpk) 1,[Pt (dpk)(ebde)] and of 2, 3-bis (2-pyridyl) pyrazine (bpp) 2,[Pt …

A brief overview is given of platinum anticancer drugs in routine clinical use and under
clinical development worldwide. Details of the binding of these drugs with nucleic acids, the …

A brief overview of mechanistic studies on the reactions of different Pt (II) complexes with
nitrogen-and sulfur-donor biomolecules is presented. The first part describes the results …

Relatively little is known about the kinetics or the pharmacological potential of
organometallic complexes of osmium compared to its lighter congeners, iron and ruthenium …

Four Pt (II) complexes with 2-H/or-methyl/or-aminomethylbenzimidazole or 1, 2-
dimethylbenzimidazole ligands as “non-leaving groups” were synthesized and their …

In this work, we have developed redox-responsive platinum (II) prodrug micelles based on
folate-poly (ethylene glycol)-b-poly (α-Pt (II)-SS-caprolactone/caprolactone)(FA-PEG-bP (α …

In this study, six Pt (II) complexes bearing 5 (6)-H or–CH3-2-phenyl or-(2′-pyridyl) or-
mercaptomethylbenzimidazole ligands as 'carrier groups' were synthesized and …

The synthesis and characterization of complexes [(η 6-arene) Ru (N, N′) X][PF 6], where
arene is para-cymene (p-cym), biphenyl (bip), ethyl benzoate (etb), hexamethylbenzene …