An overview of preclinical models of traumatic brain injury (TBI): relevance to pathophysiological mechanisms

A Fesharaki-Zadeh, D Datta - Frontiers in cellular neuroscience, 2024 - frontiersin.org
Background Traumatic brain injury (TBI) is a major cause of morbidity and mortality, affecting
millions annually worldwide. Although the majority of TBI patients return to premorbid …

[HTML][HTML] Exploring Astrocyte-Mediated Mechanisms in Sleep Disorders and Comorbidity

Y Li, M Que, X Wang, G Zhan, Z Zhou, X Luo, S Li - Biomedicines, 2023 - mdpi.com
Astrocytes, the most abundant cells in the brain, are integral to sleep regulation. In the
context of a healthy neural environment, these glial cells exert a profound influence on the …

[HTML][HTML] β-hydroxybutyrate alleviates neurological deficits by restoring glymphatic and inflammation after subarachnoid hemorrhage in mice

X Tan, X Li, R Li, W Meng, Z Xie, J Li, Y Pang… - Experimental …, 2024 - Elsevier
Background Both glymphatic system dysfunction and inflammatory response aggravate
neurological dysfunction after subarachnoid hemorrhage (SAH). Studies have shown that β …

Exploring neurodegenerative disorders using advanced magnetic resonance imaging of the glymphatic system

J Prasuhn, J Xu, J Hua, P van Zijl, L Knutsson - Frontiers in Psychiatry, 2024 - frontiersin.org
The glymphatic system, a macroscopic waste clearance system in the brain, is crucial for
maintaining neural health. It facilitates the exchange of cerebrospinal and interstitial fluid …

Brain Fluid Clearance After Traumatic Brain Injury Measured Using Dynamic Positron Emission Tomography

T Butler, J Schubert, NA Karakatsanis… - Neurotrauma …, 2024 - liebertpub.com
Brain fluid clearance by pathways including the recently described paravascular glymphatic
system is a critical homeostatic mechanism by which metabolic products, toxins, and other …

Longitudinal Assessment of Glymphatic Changes Following Mild Traumatic Brain Injury: Insights from PVS burden and DTI-ALPS Imaging

J Zhuo, P Raghavan, L Jiang, S Roys… - medRxiv, 2024 - medrxiv.org
Traumatic brain injury (TBI) even in the mild form may result in long-lasting post-concussion
symptoms. TBI is also a known risk to late-life neurodegeneration. Recent studies suggest …

[HTML][HTML] Advancement in modulation of brain extracellular space and unlocking its potential for intervention of neurological diseases

Y Yong, Y Cai, J Lin, L Ma, HB Han, F Li - Med-X, 2024 - Springer
Cells in the brain are surrounded by extracellular space (ECS), which forms porous nets and
interconnected routes for molecule transportation. Our view of brain ECS has changed from …

Advances in Multimodal Functional Optoacoustic-Fluorescence Neuroimaging

S Shaykevich - 2024 - search.proquest.com
The brain comprises billions of microscopic neurons which form long-distance networks;
therefore, understanding neural function requires investigation of processes at a range of …

[HTML][HTML] Optimal Timing of Cranioplasty After Decompressive Craniectomy: Timing or Collapse Ratio

H Huo, Y Lu, J Lu, X Wang, Z Wang… - Operative …, 2022 - journals.lww.com
METHODS: We conducted a retrospective analysis of all CP cases performed in our
department from August 2015 to March 2022. Data were gathered through case statistics …

[PDF][PDF] Cerebrospinal Fluid and Brain Health: Optimized By Grounding

L Koniver - American J Neurol Res, 2023 - intuition-physician.com
The function of the cerebrospinal fluid of our central nervous system has historically been
viewed as providing cushioning, buoyancy and a layer of physical protection to our brain …