[HTML][HTML] Current understanding of hexavalent chromium [Cr (VI)] neurotoxicity and new perspectives

JP Wise Jr, JL Young, J Cai, L Cai - Environment international, 2022 - Elsevier
Abstract Hexavalent chromium [Cr (VI)] is a global environmental pollutant that increases
risk for several types of cancers and is increasingly being recognized as a neurotoxicant …

The neurotoxicity of iron, copper and manganese in Parkinson's and Wilson's diseases

P Dusek, PM Roos, T Litwin, SA Schneider… - Journal of trace …, 2015 - Elsevier
Impaired cellular homeostasis of metals, particularly of Cu, Fe and Mn may trigger
neurodegeneration through various mechanisms, notably induction of oxidative stress …

Environmental exposure of the general population to cadmium as a risk factor of the damage to the nervous system: A critical review of current data

A Ruczaj, MM Brzóska - Journal of Applied Toxicology, 2023 - Wiley Online Library
Nowadays, more and more attention has been focused on the risk of the neurotoxic action of
cadmium (Cd) under environmental exposure. Due to the growing incidence of nervous …

[HTML][HTML] Facets of ICP-MS and their potential in the medical sciences—Part 1: fundamentals, stand-alone and hyphenated techniques

D Clases, R Gonzalez de Vega - Analytical and Bioanalytical Chemistry, 2022 - Springer
Since its inception in the early 80s, inductively coupled plasma–mass spectrometry has
developed to the method of choice for the analysis of elements in complex biological …

Iron levels in the human brain: a post-mortem study of anatomical region differences and age-related changes

P Ramos, A Santos, NR Pinto, R Mendes… - Journal of Trace …, 2014 - Elsevier
The link between brain iron homeostasis and neurodegenerative disease has been the
subject of extensive research. There is increasing evidence of iron accumulation during …

Metal exposure and risk of Parkinson disease: a systematic review and meta-analysis

Y Zhao, A Ray, L Portengen… - American Journal of …, 2023 - academic.oup.com
Metal exposure has been suggested as a possible environmental risk factor for Parkinson
disease (PD). We searched the PubMed, EMBASE, and Cochrane databases to …

[HTML][HTML] Synaptic zinc: an emerging player in Parkinson's disease

J Sikora, AM Ouagazzal - International journal of molecular sciences, 2021 - mdpi.com
Alterations of zinc homeostasis have long been implicated in Parkinson's disease (PD). Zinc
plays a complex role as both deficiency and excess of intracellular zinc levels have been …

[HTML][HTML] The assessment of the usability of selected instrumental techniques for the elemental analysis of biomedical samples

K Planeta, A Kubala-Kukus, A Drozdz, K Matusiak… - Scientific Reports, 2021 - nature.com
The fundamental role of major, minor and trace elements in different physiological and
pathological processes occurring in living organism makes that elemental analysis of …

High-precision isotopic analysis of essential mineral elements in biomedicine: natural isotope ratio variations as potential diagnostic and/or prognostic markers

M Costas-Rodríguez, J Delanghe… - TrAC Trends in Analytical …, 2016 - Elsevier
High-precision isotopic analysis of essential mineral elements, mainly Ca, Cu, Fe and Zn,
provides relevant biomedical information. For this application, multi-collector ICP-mass …

Coordination Features and Affinity of the Cu2+ Site in the α-Synuclein Protein of Parkinson's Disease

CG Dudzik, ED Walter, GL Millhauser - Biochemistry, 2011 - ACS Publications
Parkinson's disease (PD) is the second most prevalent age-related, neurodegenerative
disorder, affecting> 1% of the population over the age of 60. PD pathology is marked by …