The study of botulinum neurotoxins (BoNT) is rapidly progressing in many aspects. Novel
BoNTs are being discovered owing to next generation sequencing, but their biologic and …

During the past 25 years, botulinum toxin type A (BoNT-A) has become the most widely used
medical intervention in children with cerebral palsy. In this review we consider the gaps in …

Metalloenzymes are central to a wide range of essential biological activities, including
nucleic acid modification, protein degradation, and many others. The role of metalloenzymes …

Botulinum neurotoxins (BoNTs) are produced by anaerobic bacteria of the genus
Clostridium and cause a persistent paralysis of peripheral nerve terminals, which is known …

Botulinum neurotoxins are known to have seven serotypes (BoNT/A–G). Here we report a
new BoNT serotype, tentatively named BoNT/X, which has the lowest sequence identity with …

Botulinum neurotoxins (BoNTs) and tetanus neurotoxin (TeNT) are the most potent toxins
known and cause botulism and tetanus, respectively. BoNTs are also widely utilized as …

Chronic pelvic pain is a frustrating symptom for patients with endometriosis and is frequently
refractory to hormonal and surgical management. While these therapies target ectopic …

Botulinum neurotoxins (BoNTs), produced by various Clostridium strains, are a family of
potent bacterial toxins and potential bioterrorism agents. Here we report that an …

Botulinum neurotoxin type-A (BoNT-A) blocks the release of acetylcholine from peripheral
cholinergic nerve terminals and is an important option for the treatment of disorders …

The lack of an adequate therapy for Alzheimer's Disease (AD) contributes greatly to the
continuous growing amount of papers and reviews, reflecting the important efforts made by …