Potential pre-activation strategies for improving therapeutic efficacy of mesenchymal stem cells: current status and future prospects

M Li, Y Jiang, Q Hou, Y Zhao, L Zhong, X Fu - Stem cell research & …, 2022 - Springer
Mesenchymal stem cell (MSC)-based therapy has been considered as a promising
approach targeting a variety of intractable diseases due to remarkable multiple effect of …

Targeted therapy for inflammatory diseases with mesenchymal stem cells and their derived exosomes: from basic to clinics

S Wang, B Lei, E Zhang, P Gong, J Gu… - International Journal …, 2022 - Taylor & Francis
Inflammation is a beneficial and physiological process, but there are a number of
inflammatory diseases which have detrimental effects on the body. In addition, the drugs …

Cellular modifications and biomaterial design to improve mesenchymal stem cell transplantation

JKU Wong, A Mehta, TT Vũ, GC Yeo - Biomaterials Science, 2023 - pubs.rsc.org
Research has advanced considerably since the first clinical trial of human mesenchymal
stem cells (MSCs) in the early 1990s. During this period, our understanding of MSC biology …

Transplantation of induced pluripotent stem cells-derived cardiomyocytes combined with modified Taohong Siwu decoction improved heart repair after myocardial …

Z Luo, W Meng, H Li, Y Wang, Y Wang, Y Zhao, P Lu… - Heliyon, 2024 - cell.com
Objective This study aimed to study whether modified Taohong Siwu decoction (MTHSWD)
combined with human induced pluripotent stem cells-derived cardiomyocytes (iPS-CMs) …

Stem cell therapy against ischemic heart disease

IT Tsai, CK Sun - International Journal of Molecular Sciences, 2024 - mdpi.com
Ischemic heart disease, which is one of the top killers worldwide, encompasses a series of
heart problems stemming from a compromised coronary blood supply to the myocardium …

[HTML][HTML] Strategies to improve the effect of mesenchymal stem cell therapy on inflammatory bowel disease

MY Shi, L Liu, FY Yang - World Journal of Stem Cells, 2022 - ncbi.nlm.nih.gov
Inflammatory bowel disease (IBD) includes Crohn's disease and ulcerative colitis and is an
idiopathic, chronic inflammatory disease of the colonic mucosa. The occurrence of IBD …

Unveiling the microbiome of hydroponically cultivated lettuce: impact of Phytophthora cryptogea infection on plant-associated microorganisms

L Vlasselaer, S Crauwels, B Lievens… - FEMS Microbiology …, 2024 - academic.oup.com
Understanding the complex interactions between plants and their associated
microorganisms is crucial for optimizing plant health and productivity. While microbiomes of …

The use of stem cells as a potential treatment method for selected neurodegenerative diseases

E Cecerska-Heryć, M Pękała, N Serwin… - Cellular and Molecular …, 2023 - Springer
Stem cells have been the subject of research for years due to their enormous therapeutic
potential. Most neurological diseases such as multiple sclerosis (MS), amyotrophic lateral …

Knockdown SENP1 Suppressed the Angiogenic Potential of Mesenchymal Stem Cells by Impacting CXCR4-Regulated MRTF-A SUMOylation and CCN1 Expression

R Zhang, Q Liu, C Lyu, X Gao, W Ma - Biomedicines, 2023 - mdpi.com
The angiogenic potential of mesenchymal stem cells (MSCs) is critical for adult vascular
regeneration and repair, which is regulated by various growth factors and cytokines. In the …

Possibilities and efficiency of MSC co-transfection for gene therapy

S Christoffers, L Seiler, E Wiebe, C Blume - Stem Cell Research & Therapy, 2024 - Springer
Mesenchymal stem/stromal cells (MSCs) are not only capable of self-renewal, trans-
differentiation, homing to damaged tissue sites and immunomodulation by secretion of …