Chlamydial plasmid-dependent pathogenicity

G Zhong - Trends in microbiology, 2017 - cell.com
Most Chlamydia species carry a 7.5 kb plasmid encoding eight open reading frames
conventionally called plasmid glycoproteins 1–8 or pGP1–8. Although the plasmid is not …

[HTML][HTML] Chlamydia psittaci plasmid-encoded CPSIT_P7 induces macrophage polarization to enhance the antibacterial response through TLR4-mediated MAPK and …

S He, C Wang, Y Huang, S Lu, W Li, N Ding… - … et Biophysica Acta (BBA …, 2022 - Elsevier
Although the protective effects of Chlamydia psittaci plasmid-encoded protein CPSIT_P7 as
vaccine antigens to against chlamydial infection have been confirmed in our previous study …

[HTML][HTML] Efficacy of Pgp3 vaccination for Chlamydia urogenital tract infection depends on its native conformation

B Peng, S Zhong, Y Hua, Q Luo, W Dong… - Frontiers in …, 2022 - frontiersin.org
Urogenital tract infections with Chlamydia trachomatis have frequently been detected among
patients diagnosed with sexually transmitted infections, and such infections lead to …

[HTML][HTML] Whole genome sequencing characteristics of Chlamydia psittaci caprine AMK-16 strain, a promising killed whole cell veterinary vaccine candidate against …

VA Feodorova, SS Zaitsev, AM Lyapina… - Plos one, 2023 - journals.plos.org
Chlamydia psittaci is a primary zoonotic pathogen with a broad host range causing severe
respiratory and reproductive system infection in animals and humans. To reduce the global …

[HTML][HTML] Protective immunity induced by recombinant protein CPSIT_p8 of Chlamydia psittaci

M Liang, Y Wen, O Ran, L Chen, C Wang, L Li… - Applied microbiology …, 2016 - Springer
Chlamydia psittaci is a zoonotic pathogen with a broad host range that can lead to severe
respiratory and systemic disease in humans. Currently, an effective commercial vaccine …

[HTML][HTML] A recombinant multi-epitope peptide vaccine based on MOMP and CPSIT_p6 protein protects against Chlamydia psittaci lung infection

Y Li, K Zheng, Y Tan, Y Wen, C Wang, Q Chen… - Applied microbiology …, 2019 - Springer
Chlamydia psittaci is an obligate intracellular pathogen with a broad host range that can
lead to severe infectious disease by transferring from birds to humans. Vaccination has been …

Reduced Endometrial Ascension and Enhanced Reinfection Associated With Immunoglobulin G Antibodies to Specific Chlamydia trachomatis Proteins in Women at …

C Liu, K Hufnagel, CM O'Connell… - The Journal of …, 2022 - academic.oup.com
Background Previous research revealed antibodies targeting Chlamydia trachomatis
elementary bodies was not associated with reduced endometrial or incident infection in C …

[HTML][HTML] Protective Immunity against Chlamydia psittaci Lung Infection Induced by a DNA Plasmid Vaccine Carrying CPSIT_p7 Gene Inhibits Dissemination in BALB …

C Wang, Y Jin, J Wang, K Zheng, A Lei, C Lu… - International Journal of …, 2023 - mdpi.com
Chlamydia psittaci (C. psittaci), a zoonotic pathogen, poses a potential threat to public health
security and the development of animal husbandry. Vaccine-based preventative measures …

Safety and immunogenicity of a prototype anti-Chlamydia pecorum recombinant protein vaccine in lambs and pregnant ewes

M Desclozeaux, M Jelocnik, K Whitting, S Saifzadeh… - Vaccine, 2017 - Elsevier
Arthritis and kerato-conjunctivitis caused by Chlamydia pecorum in lambs are difficult to
diagnose and treat. We tested the ability of a prototype C. pecorum vaccine (SC-vaccine) …

Evaluation of a tandem Chlamydia psittaci Pgp3 multiepitope peptide vaccine against a pulmonary chlamydial challenge in mice

C Wang, Y Li, S Wang, X Yan, J Xiao, Y Chen… - Microbial …, 2020 - Elsevier
Chlamydia psittaci is the pathogen of psittacosis, and it has emerged as a significant public
health threat. Because most infections are easily overlooked, a vaccine is recognized as the …