Serotonin (5-hydroxytryptamine, 5-HT) is probably unique among the monoamines in that its
effects are subserved by as many as 13 distinct heptahelical, G-protein-coupled receptors …

The 5-HT3 receptor is a member of the Cys-loop family of ligand-gated ion channels. These
receptors are located in both the peripheral and central nervous systems, where functional …

Molecular biology has dramatically advanced our knowledge and understanding of
receptors for 5-hydroxytryptamine (5-HT). The existence of multiple 5-HT receptors defined …

Neurotransmitter regulation of bone metabolism has been the subject of increasing interest
and investigation. Because serotonin (5-HT) plays a role as a regulator of craniofacial …

The ligand-gated ion channel superfamily of neurotransmitter receptors are proteins
responsible for rapid transmission of nerve impulses at the synapse and have, therefore …

Following the cloning and sequencing of the A subunit of the 5‐HT3 receptor, two
alternatively spliced isoforms, 5‐HT3‐AS and 5‐HT3‐AL, have been identified. In order to …

5-HT3-receptor antagonists are highly selective competitive inhibitors of the 5-HT3-receptor
withnegligible affinity for other receptors. They are potent, rapidly absorbed and easily …

The serotonergic mechanisms have been successfully utilized by the majority of
antidepressant drug discovery programmes, while the search for newer targets remains …

Serotonin (5-hydroxytryptamine, 5-HT), next to being an important neurotransmitter, recently
gained attention as a key-regulator of pre-and postnatal development in the mammalian …

Abstract Serotonin (5-HT) 5-HT 3 receptors are ligand-gated ion channels, which are
generally thought to be involved in the presynaptic modulation of neurotransmitter release …