The central nucleus of the amygdala and the construction of defensive modes across the threat-imminence continuum
JM Moscarello, MA Penzo - Nature Neuroscience, 2022 - nature.com
In nature, animals display defensive behaviors that reflect the spatiotemporal distance of
threats. Laboratory-based paradigms that elicit specific defensive responses in rodents have …
threats. Laboratory-based paradigms that elicit specific defensive responses in rodents have …
Brainstem circuits for locomotion
Locomotion is a universal motor behavior that is expressed as the output of many integrated
brain functions. Locomotion is organized at several levels of the nervous system, with …
brain functions. Locomotion is organized at several levels of the nervous system, with …
Basal ganglia–spinal cord pathway that commands locomotor gait asymmetries in mice
The basal ganglia are essential for executing motor actions. How the basal ganglia engage
spinal motor networks has remained elusive. Medullary Chx10 gigantocellular (Gi) neurons …
spinal motor networks has remained elusive. Medullary Chx10 gigantocellular (Gi) neurons …
Defensive responses: Behaviour, the brain and the body
YT Tseng, B Schaefke, P Wei, L Wang - Nature Reviews Neuroscience, 2023 - nature.com
Most animals live under constant threat from predators, and predation has been a major
selective force in shaping animal behaviour. Nevertheless, defence responses against …
selective force in shaping animal behaviour. Nevertheless, defence responses against …
[HTML][HTML] A neuropeptidergic circuit gates selective escape behavior of Drosophila larvae
BN Imambocus, F Zhou, A Formozov, A Wittich… - Current Biology, 2022 - cell.com
Animals display selective escape behaviors when faced with environmental threats.
Selection of the appropriate response by the underlying neuronal network is key to …
Selection of the appropriate response by the underlying neuronal network is key to …
Flexible inhibitory control of visually evoked defensive behavior by the ventral lateral geniculate nucleus
A Fratzl, AM Koltchev, N Vissers, YL Tan… - Neuron, 2021 - cell.com
Animals can choose to act upon, or to ignore, sensory stimuli, depending on circumstance
and prior knowledge. This flexibility is thought to depend on neural inhibition, through …
and prior knowledge. This flexibility is thought to depend on neural inhibition, through …
[HTML][HTML] The aging mouse brain: cognition, connectivity and calcium
CI Radulescu, V Cerar, P Haslehurst, M Kopanitsa… - Cell calcium, 2021 - Elsevier
Aging is a complex process that differentially impacts multiple cognitive, sensory, neuronal
and molecular processes. Technological innovations now allow for parallel investigation of …
and molecular processes. Technological innovations now allow for parallel investigation of …
Mechanically evoked defensive attack is controlled by GABAergic neurons in the anterior hypothalamic nucleus
Innate defensive behaviors triggered by environmental threats are important for animal
survival. Among these behaviors, defensive attack toward threatening stimuli (for example …
survival. Among these behaviors, defensive attack toward threatening stimuli (for example …
A cortico-collicular circuit for orienting to shelter during escape
D Campagner, R Vale, YL Tan, P Iordanidou… - Nature, 2023 - nature.com
When faced with predatory threats, escape towards shelter is an adaptive action that offers
long-term protection against the attacker. Animals rely on knowledge of safe locations in the …
long-term protection against the attacker. Animals rely on knowledge of safe locations in the …
Divergent outputs of the ventral lateral geniculate nucleus mediate visually evoked defensive behaviors
LD Salay, AD Huberman - Cell reports, 2021 - cell.com
Rapid alternations between exploration and defensive reactions require ongoing risk
assessment. How visual cues and internal states flexibly modulate the selection of behaviors …
assessment. How visual cues and internal states flexibly modulate the selection of behaviors …